Traffic-related organic and inorganic air pollution and risk of development of childhood asthma: A meta-analysis

Han, Kun; Zheng, Ran; Wang, Xiuyan; Wu, Qiong; Zhan, N.Y.; Yi, Zhongqin; Jin, Taosheng

doi:10.1016/j.envres.2020.110493

Cited by 52 publications

(21 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The variations in findings in terms of air pollution and the origin of asthma in children are still not completely understood [52,53,54]. The results suggest that asthma initiation and/or modulation effects and the relationships with air pollution may be complex and nonlinearly dependent [15,55].…”

Section: Discussionmentioning

confidence: 99%

Indoor air pollution effects on pediatric asthma are submicron aerosol particle–dependent

et al. 2022

View full text Add to dashboard Cite

Up to day, only a few studies evaluated the influence of the school environment on the respiratory health of younger schoolage children. At the same time, there is a shortage of studies analyzing the effects of different size range aerosol pollutants. When children enter the first grade of primary school, they are relatively naive to air pollution other than in the home environment. Therefore, children in this age group were chosen as the target group. Our study aimed to evaluate indoor air pollution particle number and mass concentrations in primary schools and the impact of different size range particles on asthma morbidity among younger school-age children.

show abstract

Section: Discussionmentioning

confidence: 99%

Indoor air pollution effects on pediatric asthma are submicron aerosol particle–dependent

et al. 2022

View full text Add to dashboard Cite

show abstract

“…A recent overview of systematic reviews and meta-analysis that focused on children's TRAP exposures as a potential cause for asthma development found an increased risk of 7% for PM2.5, 11% for NO 2 , 21% for benzene, and 6% for TVOCs. 32 Additionally, DEP exposure at age one was positively associated with aeroallergen sensitization at ages two and three. 33 Compared with NO 2 , PM2.5 has been more strongly associated with outdoor aeroallergen sensitization while exposure to both NO 2 and PM2.5 has been significantly associated with food sensitization at the age of 4 and 8 years.…”

Section: Traffic-related Air Pollution and Childhood Asthmamentioning

confidence: 96%

“…These findings are limited by diverse definitions in exposure (land‐use regression/dispersion models and roadway proximity), outcomes (asthma symptoms, asthma diagnosis, wheeze phenotypes, or allergic sensitization), unmeasured confounding of other factors (environmental allergens, climate, diet, physical activity or socioeconomic) and their complex interactions that drive allergic disease and modify the effects of TRAP exposure. A recent overview of systematic reviews and meta‐analysis that focused on children's TRAP exposures as a potential cause for asthma development found an increased risk of 7% for PM2.5, 11% for NO 2 , 21% for benzene, and 6% for TVOCs 32 . Additionally, DEP exposure at age one was positively associated with aeroallergen sensitization at ages two and three 33 .…”

Section: Environmental Pollutants As Determinants Of Childhood Asthmamentioning

confidence: 99%

Environmental inequality: Air pollution and asthma in children

Paciência

Rufo

Moreira

2022

Pediatric Allergy Immunology

View full text Add to dashboard Cite

Dirty air is now recognized as the single biggest environmental threat to human health. 1 The air we breathe is becoming increasingly polluted and its impact on health is appraised to be as great as other major global health risks such as unhealthy diet, sedentarism, or tobacco. Nonetheless, air pollution is hard to escape. An emerging body of evidence emphasizes the associations between poorquality environments and socioeconomic conditions at both local and regional scales. 2 Whether you benefit from high-quality urban

show abstract

“…These findings are limited by diverse definitions in exposure (land-use regression/dispersion models and roadway proximity), outcomes (asthma symptoms, asthma diagnosis, wheeze phenotypes or allergic sensitization), unmeasured confounding of other factors (environmental allergens, climate, diet, physical activity or socioeconomic) and their complex interactions that drive allergic disease and modify the effects of TRAP exposure. A recent overview of systematic reviews and meta-analysis that focused on children's TRAP exposures as a potential cause for asthma development found an increased risk of 7% for PM2.5, 11% for NO2, 21% for benzene and 6% for TVOCs [32]. Additionally, DEP exposure at age one was positively associated with aeroallergen sensitization at ages two and three [33].…”

Section: Traffic-related Air Pollution and Childhood Asthmamentioning

confidence: 99%

Environmental inequality: air pollution and asthma in children

Paciência

Rufo

Moreira

2022

Preprint

View full text Add to dashboard Cite

Whether you benefit from high-quality urban environments, such as those rich in green and blue spaces, that may offer benefits to allergic and respiratory health depends on where you live and work. Environmental inequality, therefore, results from the unequal distribution of the risks and benefits that stem from interactions with our environment. Within this perspective, this article reviews the evidence for an association between air pollution caused by industrial activities, traffic, disinfection-by-products and tobacco/e-cigarettes and asthma in children. We also discuss the proposed mechanisms by which air pollution increases asthma risk, including environmental epigenetic regulations, oxidative stress, and damage, disrupted barrier integrity, inflammatory pathways, and enhancement of respiratory sensitization to aeroallergens. Environmental air pollution is a major determinant of childhood asthma, but magnitude of effect is not shared equally across the population, regions, and settings where people live, work, and spend their time. Improvement of the exposure assessment, a better understanding of critical exposure time windows, underlying mechanisms, and drivers of heterogeneity may improve the risk estimates. Urban conditions and air quality are not only important features for national and local authorities to shape healthy cities and protect their citizens from environmental and health risks, but they also provide opportunities to mitigate inequalities in the most deprived areas where the environmental burden is highest. Actions to avoid exposure to indoor and outdoor air pollutants should be complementary at different levels – individual, local, and national levels – to take effective measures to protect children who have little or no control over the air they breathe.

show abstract

Traffic-related organic and inorganic air pollution and risk of development of childhood asthma: A meta-analysis

Cited by 52 publications

References 49 publications

Indoor air pollution effects on pediatric asthma are submicron aerosol particle–dependent

Indoor air pollution effects on pediatric asthma are submicron aerosol particle–dependent

Environmental inequality: Air pollution and asthma in children

Environmental inequality: air pollution and asthma in children

Contact Info

Product

Resources

About