Adolescent is the most important period in one's life. It is a period of stress and strain of day dreams, of intense affection and excitement. Learning is a process of bringing relatively permanent change in behavior of the learner through experience or practice. Learning problems are the common thing found among all the age groups, professions, etc. The aim of this research is to assess the learning problems among first year B.Sc. Nursing students. Moreover, to identify the association between learning problems and related demographic variables of the data set. For this study a descriptive quantitative method was used to meet the objectives. Chi square value computed between learning problems and medium of instruction in higher secondary school at degree of freedom 2 was significant at 0.05 levels. We have observed that there is an association between learning problems, medium of instruction and average number of hours spend per day for the study.Similarly, the learning problems and average number of hours spend per day for the study at degree of freedom 2, was significant at 0.05 levels.