Training rats to search and alert on contraband odors

Otto, James; Brown, Michael F.

doi:10.1016/s0168-1591(02)00052-7

Cited by 23 publications

(12 citation statements)

References 4 publications

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“…Other animals have also been studied to establish any suitability for vapour detection. Rats have a sensitive and discriminating olfactory system and have been shown to correctly discriminate between odours and alert when explosives are present using a remote monitoring technique [59]. Insects, such as Drosophila melanogaster, have also been investigated due to the capability they have to detect a large range of odours and the simple olfactory system they possess.…”

Section: Animalsmentioning

confidence: 99%

Current trends in explosive detection techniques

Caygill

Davis

Higson

2012

Talanta

453

258

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The detection of explosives and explosive-related compounds has become a heightened priority in recent years for homeland security and counter-terrorism applications. There has been a huge increase in research within this area-through both the development of new, innovative detection approaches and the improvement of existing techniques. Developments for miniaturisation, portability, field-ruggedisation and improvements in stand-off distances, selectivity and sensitivity have been necessary to develop and improve techniques. This review provides a consolidation of information relating to recent advances in explosive detection techniques without being limited to one specific research area or explosive type. The focus of this review will be towards advances in the last 5 years, with the reader being referred to earlier reviews where appropriate.

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Section: Animalsmentioning

confidence: 99%

Current trends in explosive detection techniques

Caygill

Davis

Higson

2012

Talanta

453

258

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“…Primates distinguish many enantiomer pairs (19). Bees (20), rats and dogs can detect specific molecules in explosives (21) and contraband (22), while dogs can sniff out bladder cancers from urine samples (23). Such specificity alone supports the idea that the olfactory sense of a suitably sensitive person could distinguish between different molecules binding to different enzyme active sites, i.e.…”

mentioning

confidence: 99%

Traditional Phytochemistry: Identification of Drug by ‘Taste’

Joshi

Hankey²,

Patwardhan³

2006

Evidence-Based Complementary and Alternative Medicine

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Ayurveda, the system of traditional medicine from India, holds that ‘Rasa’, a concept roughly corresponding to taste, is a basis for identifying pharmacological properties of plants and other materia medica used in Dravyaguna—its system of phytomedicine. This idea has recently found support in studies of ibuprofen, the pharmacological properties of which are similar to those of oleocanthal, because the two substances have very similar tastes. This paper discusses a possible scientific approach to understanding the Ayurvedic (hypo)thesis in terms of the stereochemical basis of both pharamaco-activity and taste, and the numbers of possible pharmaco-active compounds that ‘Rasa’ may be able to distinguish. We conclude that molecules binding to a specific enzyme active site should have their own ‘Rasa’, and that the number of different subjectively experienced ‘tastes’ is more than enough to distinguish between molecular shapes binding to all enzyme active sites in the body.

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“…Experiments with the Common Brown Rat (Rattus norvegicus) demonstrated that rats can learn to exhibit unique alerting behaviors upon identification of a variety of odors [72]. Other studies with the African Giant Pouched Rat (Cricetomys gambianus) demonstrated that the use of rats to evaluate land mine risk is a very promising mine-detection method [73].…”

Section: Ratsmentioning

confidence: 99%

The Development of an Optimized System of Narcotic and Explosive Contraband Mimics for Calibration and Training of Biological Detectors

Macias¹

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Training rats to search and alert on contraband odors

Cited by 23 publications

References 4 publications

Current trends in explosive detection techniques

Current trends in explosive detection techniques

Traditional Phytochemistry: Identification of Drug by ‘Taste’

The Development of an Optimized System of Narcotic and Explosive Contraband Mimics for Calibration and Training of Biological Detectors

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