2022
DOI: 10.1101/2022.11.12.516261
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Trait salivary alpha-amylase activity levels define the conditions for facilitation by L-DOPA of extinction consolidation

Abstract: Even after successful extinction, conditioned fear can return. Strengthening the consolidation of the fear-inhibitory safety memory formed during extinction is one way to counteract return of fear. In this preregistered direct replication study, we confirm that spontaneous post-extinction reactivations of a neural activation pattern evoked in the ventromedial prefrontal cortex (vmPFC) during extinction predict extinction memory retrieval 24 h later. We do not confirm that L-DOPA administration after extinction… Show more

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