Trajectories of body mass index in adulthood and all-cause and cause-specific mortality in the Melbourne Collaborative Cohort Study

Yang, Yi; Dugué, Pierre-Antoine; Lynch, Brigid M.; Hodge, Allison; Karahalios, Amalia; MacInnis, Robert J.; Milne, Roger L.; Giles, Graham G.; English, Dallas R.

doi:10.1136/bmjopen-2019-030078

Cited by 40 publications

(56 citation statements)

References 53 publications

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“…Our data are similar to other Asian countries such as Japan (5), where the mid-normal weight group comprises 67.1% of the population. Second, body weight status does not seem to vary across the lifetime in our sample, which is similar to studies in Japan(5), but different in US and Austrian studies (22)(23)(24). Asian populations may be different from Western populations on the issue of BMI trajectory.…”

Section: Discussionsupporting

confidence: 78%

BMI Trajectory In Relation to Cause-Specific Mortality In Taiwan’s Adult Population.

Ch'iu

Kukreti

et al. 2021

Preprint

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Background: A dynamic change in weight over time has been known as an important factor that impacts mortality risk. However, it is currently unknown how the dynamic change of body mass index (BMI) contributes to the cause-specific mortality risk.Methods: In this cohort study, we obtained data from a large prospective cohort study in Taiwan between 1998 and 2019, which was linked to National Death Registry for death information. The database accumulated 290,279 participants who were born before 1977. We excluded those who were less than 40 years old at 1998 (n=51,731), less than two waves follow-up (n=145,270), and who had ever been diagnosed at baseline with any of the following self-reported conditions: cancer, stroke (n=3392) with a final 89,886 participants.Results: This study shows that different trajectories are associated with mortality suggests that the mortality risk differs in each trajectory group and in each age and gender stratification. It appears that obesity is a protective factor in cancer-related mortality in females but not in males in the group of old age; low-normal weight is a risk factor in respiratory-related mortality in all participants.Conclusions: Our findings can be used to define the appropriate BMI in each age and gender groups and thereby earlier health interventions can be taken to avoid mortality.

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Section: Discussionsupporting

confidence: 78%

BMI Trajectory In Relation to Cause-Specific Mortality In Taiwan’s Adult Population.

Ch'iu

Kukreti

et al. 2021

Preprint

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“…We also compared trends in age-specific DKOLH-CVD death rates with a measure of cohort relative lifetime obesity prevalence to reflect the increased risk of mortality where BMI is high throughout the life course [35]. Using GBD obesity prevalence estimates from 1980 to 2015 by year, sex, and 5-year age groups, we calculated relative obesity prevalence for each 5-year cohort based on age at the most recent year of mortality data.…”

Section: Methodsmentioning

confidence: 99%

The role of overweight and obesity in adverse cardiovascular disease mortality trends: an analysis of multiple cause of death data from Australia and the USA

Adair

López

2020

BMC Med

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Background: In recent years, there have been adverse trends in premature cardiovascular disease (CVD) mortality rates (35-74 years) in the USA and Australia. Following long-term declines, rates in the USA are now increasing while falls in Australia have slowed rapidly. These two countries also have the highest adult obesity prevalence of high-income countries. This study investigates the role of overweight and obesity in their recent CVD mortality trends by using multiple cause of death (MCOD) data-direct individual-level evidence from death certificatesand linking the findings to cohort lifetime obesity prevalence. Methods: We identified overweight-and obesity-related mortality as any CVD reported on the death certificate (CVD MCOD) with one or more of diabetes, chronic kidney disease, obesity, lipidemias or hypertensive heart disease (DKOLH-CVD), causes strongly associated with overweight and obesity. DKOLH-CVD comprises 50% of US and 40% of Australian CVD MCOD mortality. Trends in premature age-standardized death rates were compared between DKOLH-CVD and other CVD MCOD deaths (non-DKOLH-CVD). Deaths from 2000 to 2017 in the USA and 2006-2016 in Australia were analyzed. Trends in in age-specific DKOLH-CVD death rates were related to cohort relative lifetime obesity prevalence. Results: Each country's DKOLH-CVD mortality rate rose by 3% per annum in the most recent year, but previous declines had reversed more rapidly in Australia. Non-DKOLH-CVD mortality in the USA increased in 2017 after declining strongly in the early 2000s, but in Australia it has continued declining in stark contrast to DKOLH-CVD. There were larger increases in DKOLH-CVD mortality rates at successively younger ages, strongly related with higher relative lifetime obesity prevalence in younger cohorts. Conclusions: The increase in DKOLH-CVD mortality in each country suggests that overweight and obesity has likely been a key driver of the recent slowdown or reversal of CVD mortality decline in both countries. The larger recent increases in DKOLH-CVD mortality and higher lifetime obesity prevalence in younger age groups are very concerning and are likely to adversely impact CVD mortality trends and hence life expectancy in future. MCOD data is a valuable but underutilized source of data to track important mortality trends.

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“…In data from 5 Nordic countries, the standardised mortality rate (SMR) of patients receiving bariatric surgery was improved compared to non-operated patients with obesity (SMR 0.63, 95% CI 0.60 to 0.66), although mortality for these patients was still significantly increased relative to the general non-obese population (SMR 1.94, 95% CI 1.83 to 2.05) [41]. Increased BMI class has been strongly associated development of disease and increased mortality risk [48][49][50]; therefore, elevated mortality relative to the general population may relate to ongoing effects of existing disease before surgery. Determining the ongoing mortality…”

Section: Plos Medicinementioning

confidence: 99%

Association of bariatric surgery with all-cause mortality and incidence of obesity-related disease at a population level: A systematic review and meta-analysis

et al. 2020

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Background Previous clinical trials and institutional studies have demonstrated that surgery for the treatment of obesity (termed bariatric or metabolic surgery) reduces all-cause mortality and the development of obesity-related diseases such as type 2 diabetes mellitus (T2DM), hypertension, and dyslipidaemia. The current study analysed large-scale population studies to assess the association of bariatric surgery with long-term mortality and incidence of newonset obesity-related disease at a national level. Methods and findings A systematic literature search of Medline (via PubMed), Embase, and Web of Science was performed. Articles were included if they were national or regional administrative database cohort studies reporting comparative risk of long-term mortality or incident obesity-related diseases for patients who have undergone any form of bariatric surgery compared with an appropriate control group with a minimum follow-up period of 18 months. Meta-analysis of hazard ratios (HRs) was performed for mortality risk, and pooled odds ratios (PORs) were calculated for discrete variables relating to incident disease. Eighteen studies were identified as suitable for inclusion. There were 1,539,904 patients included in the analysis, with 269,818 receiving bariatric surgery and 1,270,086 control patients. Bariatric surgery was associated with a reduced rate of all-cause mortality (POR 0.62, 95% CI 0.55 to 0.69, p < 0.001) and cardiovascular mortality (POR 0.50, 95% CI 0.35 to 0.71, p < 0.001). Bariatric surgery was strongly associated with reduced incidence of T2DM (POR 0.39, 95% CI 0.18 to 0.83, p = 0.010), hypertension (POR 0.36, 95% CI 0.32 to 0.40, p < 0.001), dyslipidaemia (POR 0.33, 95% CI 0.14 to 0.80, p = 0.010), and ischemic heart disease (POR 0.46, 95% CI 0.29 to 0.73, p = 0.001). Limitations of the study include that it was not possible to account for unmeasured variables, which may not have been equally distributed between patient

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Trajectories of body mass index in adulthood and all-cause and cause-specific mortality in the Melbourne Collaborative Cohort Study

Cited by 40 publications

References 53 publications

BMI Trajectory In Relation to Cause-Specific Mortality In Taiwan’s Adult Population.

BMI Trajectory In Relation to Cause-Specific Mortality In Taiwan’s Adult Population.

The role of overweight and obesity in adverse cardiovascular disease mortality trends: an analysis of multiple cause of death data from Australia and the USA

Association of bariatric surgery with all-cause mortality and incidence of obesity-related disease at a population level: A systematic review and meta-analysis

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