Tramadol and Sexual Dysfunction

Err, Hai; Wiwanitkit, Viroj

doi:10.4103/0253-7176.150859

Cited by 2 publications

(1 citation statement)

References 3 publications

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“…Both polyuria and erectile dysfunction are very uncommon side effects of tramadol, reported in <1% of people taking the drug [ 4 – 6 ]. The effects of tramadol on sexual dysfunction are relatively expected despite the apparent rarity of the side effect, as it has been used in various studies for the treatment of premature ejaculation [ 7 , 8 ]. Tramadol is an analgesic with centrally acting opioid activity (weak μ-opioid effect) in addition to inhibition of reuptake of 5-hydroxytryptamine and norepinephrine.…”

Section: Discussionmentioning

confidence: 99%

Pain management in our daily practice: should we re-evaluate?

Hassan

Chen

2015

Oxf Med Case Rep

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Treatment strategies of back pain are variable. We describe an unusual case of polyuria and erectile dysfunction with a short-term tramadol use. A 29-year-old man presented to our clinic with worsening lower back pain. After poor control of his pain on Non steroidal anti-inflammatory drugs, tramadol was prescribed. After 3 days of starting tramadol, he experienced significant polyuria and erectile dysfunction with inability to ejaculate or obtain orgasm. He denied any systemic symptoms. On follow-up, he reported complete resolution of his polyuria and erectile dysfunction within 24 h of stopping tramadol, in addition to satisfactory control of his pain. Polyuria and erectile dysfunction are very uncommon side effects of tramadol, reported in <1% of chronic users. This is the first case report to demonstrate such a rapid and aggressive onset of this combination of rare side effects with the complete resolution after tramadol discontinuation.

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