Tramadol in seized drugs containing non-pharmaceutical fentanyl: Crime lab data from Ohio, USA

Ruhter, Lance; Juhascik, Matthew P.; Sweeney, Kaylin; Daniulaityte, Raminta

doi:10.1016/j.etdah.2022.100042

Cited by 1 publication

(1 citation statement)

References 27 publications

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“…These properties make tramadol ideal for the management of postoperative pain. It was first synthesized in 1965 and introduced in the US in 1995 as a non-scheduled drug due to its low abuse potential [ 11 12 ]. However, tramadol abuse is high in Western Asian and African nations.…”

Section: Introductionmentioning

confidence: 99%

Pre-emptive analgesia efficacy of piroxicam versus tramadol in oral surgery

Muthuluri

Chandrupatla²,

Rajan

et al. 2022

J Dent Anesth Pain Med

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Background This double-blind randomized controlled trial (RCT) was conducted to evaluate the pre-emptive analgesia and anti-inflammatory efficacy of piroxicam compared with tramadol in patients undergoing oral surgery. Methods Seventy-eight patients who required extraction of impacted mandibular third molars were randomized into three treatment groups of 26 patients each: group I received 100 mg of tramadol, group II received 20 mg of piroxicam, and group III received a placebo. Drugs were administered intramuscularly 30 min prior to the extraction procedure. Results Pain intensity, time to first analgesic administration, total analgesic consumption, facial edema, and trismus were the outcomes of interest. The group receiving 20 mg of piroxicam showed significantly lower pain intensity, increased time to first analgesic, and reduced edema from preoperative to postoperative day seven than those in the tramadol and placebo groups. Conclusion The findings of this study showed that piroxicam had significant pain relief efficacy after third molar surgery compared with that in tramadol.

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Section: Introductionmentioning

confidence: 99%