Tramadol versus fentanyl during propofol‐based deep sedation for uterine dilatation and curettage: A prospective study

Taş, Ayça; Mıstanoglu, Veli; Darçın, Sevtap; Kececioglu, Melahat

doi:10.1111/jog.12259

Cited by 13 publications

(11 citation statements)

References 11 publications

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“…La duración del procedimiento de legrado uterino es de 12 ± 2,9 minutos, considerando que somos un centro de enseñanza y contamos con residentes de gineco-obstetricia en fase de entrenamiento; en este sentido, Tas y col 9 indican un tiempo del procedimiento de 5,7 ± 2,6 minutos más corto comparado al presente estudio, por los factores previamente resaltados.…”

Section: Discussionunclassified

Remifentanil y propofol con infusión controlada por objetivo para legrado uterino

Andrade¹,

Ortiz²

2020

Gac Med Bol

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Objetivo: analizar el comportamiento hemodinámico frente al manejo anestésico con remifentanilo y propofol con infusión controlada por objetivo en pacientes sometidas a legrado uterino por aborto incompleto. Métodos: se realizó un ensayo clínico no controlado utilizando un protocolo de atención aprobado por el servicio de anestesiología obstétrica del Hospital Obrero Nº2, entre enero a mayo de 2019, ingresando 39 pacientes sometidas a legrado uterino instrumental; usando el modelo Minto para remifentanil y el modelo Schnider para Propofol para la infusión controlada. La valoración de las diferencias estadísticas en los parámetros hemodinámicos se realizó mediante comparación de medias por T de student. Resultados: la edad media de las participantes del fue 34,77±7,9 años, tiempo quirúrgico de 12 ± 2,9 minutos. El tiempo anestésico de 15 ± 3 minutos; el tiempo del alta de la recuperación anestésica a salas de 14 ±3,3 minutos. La dosis de inducción del remifentanilo utilizada fue de 4,8 ± 0,3 ng/ml (p >0,001) y la dosis de inducción del propofol fue de 3,77± 0,4 mcg/ml (p >0,001). Las dosis de mantenimiento del remifentanilo de 4,56 ± 0,5 ng/ml y la dosis del propofol es de 3,8 ± 0,6 mcg/ml (p >0,001). No se encontró complicaciones ni hallazgos secundarios por el uso de los medicamentos. Conclusiones: el uso del sistema de infusión controlado por objetivo (TCI) para remifentanilo en el modelo de Minto y modelo de Schinder para el propofol proporciona a las pacientes buena estabilidad hemodinámica.

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Section: Discussionunclassified

Remifentanil y propofol con infusión controlada por objetivo para legrado uterino

Andrade¹,

Ortiz²

2020

Gac Med Bol

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“…Opiods that are used for analgesia are not common in day-case procedures because it causes respiratory depression, itching, and has long-lasting recovery period (11). In this study, we compared tramadol and ketamine which are similar in terms of analgesic efficacy and both have short recovery periods.…”

Section: Discussionmentioning

confidence: 99%

“…In addition to this, side effects of this agent such as nausea and vomiting are mentioned (10). In the study conducted by Taş et.al (11), propofol-fentanyl and propofol-tramadol were compared in patients that had dilatation and curettage. Researchers have found similar analgesic features, but they concluded that tramadol had less effect on respiration and so it could be safe.…”

Section: Discussionmentioning

confidence: 99%

A study on curettage pain and hemodynamic parameters of curettage patients: Ketamine or Tramadol?

Baltaoğlu

Darçın

2018

HumanSciences

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Aim: The aim of this study was to compare ketamin-propofol and tramadol propofol combination in patients undergoing uterine dilatation and curettage. Total propofol requirement, pain scoring and recovery period of duration. Methods: One Hundred Women undergoing uterine dilatation and curettage were screened retrospectively after ethical comitee approval. Baseline anesthesia was maintained with 1 mg/kg propofol, and the patients were randomly allocated to receive 0.5 mg/kg ketamine (Group 1, n=50) or 1 mg/kg tramadol (Group 2, n=50) thereafter. Hemodynamic variables, pain, sedation, Aldrete recovery score and side effects were recorded. Results: Postoperative heart rate and systolic arterial pressure on beginning were significantly higher in Group 1 compared with Group 2 ( p<0.05). No significant difference was noticed compared other results between the groups. Conclusion: Tramadol might be a better alternative drug rather than ketamine due to better hemodynamic stability and lower respiratory depression rate were seen in patents with it.

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“…Dikatakan bahwa tramadol memiliki potensi analgesi yang sama dengan 1/1.000 fentanil. 4 Penelitian tramadol sebagai analgetik intraoperatif pada operasi abdomen dengan dosis per kgBB sebesar 2 mg, 3 mg, dan 4 mg menunjukkan pengaruh yang sama terhadap tekanan darah dan laju nadi, tetapi dosis 4 mg/kgBB memiliki efek analgesi sampai lima jam postoperasi. 5 Tujuan penelitian ini adalah mengetahui perbandingan antara tramadol 2 mg/kgBB dan fentanil 2 µg/kgBB sebagai nalgetik intraoperatif, dilihat dari pengaruhnya terhadap skor PRST pada operasi laparotomi ginekologis.…”

Section: Pendahuluanunclassified

Perbandingan antara Tramadol 2 mg/kgBB dan Fentanil 2 mg/kgBB Intravena Sebagai Analgetik Intraoperatif pada Operasi Laparotomi Ginekologis; Pengaruhnya terhadap Skor PRST

Kurniawan¹,

Pratiwi²

2017

mkb

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AbstrakPerkembangan dan kemajuan teknologi serta ilmu pengetahuan telah mendorong pelaksanaan pelayanan kesehatan yang lebih efektif dan lebih ekonomis dibanding dengan cara yang lazim dikerjakan. Telah dilakukan penelitian di Rumah Sakit Dr. Dustira Cimahi pada bulan Juni-September 2016 terhadap 32 pasien operasi laparotomi ginekologis yang dibagi menjadi dua kelompok. Kelompok Tramadol (n=16) diberikan tramadol 2 mg/kgBB (pengenceran akuabides sampai 10 mL) lewat jalur infus selama satu menit, sedangkan pada kelompok Fentanil (n=16) diberikan fentanil 2 µg/kgBB dengan cara yang sama. Lima menit kemudian diberikan propofol 2 mg/kgBB, atrakurium 0,5 mg/kgBB, enfluran 2 volume %, N 2 O:O 2 =2 L/menit:2 L/menit. Pencatatan tekanan darah, laju nadi, saturasi O 2 , dan skor PRST dilakukan sebagai berikut: T0 = penderita tiba di kamar operasi, T1= preintubasi, T2= satu menit setelah intubasi, T3= satu menit setelah insisi, T4 dan seterusnya diukur tiap 15 menit sampai selesai operasi. Pasien diekstubasi setelah pernapasan adekuat. Skala sedasi dan muntah dinilai setiap 15 menit setelah ekstubasi selama dua jam. Dari hasil penelitian didapatkan skor PRST mulai T1 sampai T12 secara statistis tidak berbeda bermakna antara kelompok tramadol dan fentanil (p>0,05). Kedua kelompok mengalami peningkatan skor PRST satu menit setelah intubasi. Skor PRST dipertahankan antara 0 sampai 2. Pada kelompok tramadol dan fentanil masing-masing satu orang mendapatkan analgetik pertolongan fentanil 50 µg karena skor PRST 5. Tidak ditemukan perbedaan skala sedasi dan muntah antara dua kelompok perlakuan. Penelitian ini menunjukkan tramadol 2 mg/kgBB dibanding dengan fentanil 2 µg/kgBB sebagai analgetik intraoperatif pada operasi laparotomi ginekologis memberikan pengaruh yang sama terhadap skor PRST. Fentanyl as Intraoperative Analgetic in Gynecologic Laparotomy and Its Effects on PRST Score AbstractThe technological and scientific development and improvement have influenced the effectiveness and economic of health care. This study was performed in Dr. Dustira Hospital Cimahi period June to September 2016 on 32 patients undergoing gynecologic laparotomy. Subjects were divided into 2 groups with 16 patients in each group. The tramadol group was given 2 mg.kgbw-1 tramadol (diluted to 10 mL) via IV line over one minute whereas the fentanyl group received 2 µg.kgbw-1 fentanyl using the same procedure used for the tramadol group. Induction was done after five minutes with 2 mg.kgbw-1 propofol, 0.5 mg.kgbw-1 atracurium while the state of anesthesia was maintained with 2 vol.% enflurane, 50% O 2 and 50% N 2 O at 4 L/minute flow rate. Rescue analgetics in the form of 50 mcf fentanyl was prepared to be given if the PRST score was more than 4. Postoperative analgesics using 30 mg ketorolac and antiemetic 10 mg metoclopramide were given intravenously during skin closure. Blood pressure, heart rate, oxygen saturation and PRST Score were recorded at T0=patient on arrival in the theatre, T1=preintubation, T2=one minute after intubation, and T3=one min...

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Tramadol versus fentanyl during propofol‐based deep sedation for uterine dilatation and curettage: A prospective study

Abstract: Tramadol provides similar analgesic efficacy to fentanyl. Furthermore, tramadol may provide better respiratory stability in patients undergoing a D&C procedure.

Cited by 13 publications

References 11 publications

Remifentanil y propofol con infusión controlada por objetivo para legrado uterino

Remifentanil y propofol con infusión controlada por objetivo para legrado uterino

A study on curettage pain and hemodynamic parameters of curettage patients: Ketamine or Tramadol?

Perbandingan antara Tramadol 2 mg/kgBB dan Fentanil 2 mg/kgBB Intravena Sebagai Analgetik Intraoperatif pada Operasi Laparotomi Ginekologis; Pengaruhnya terhadap Skor PRST

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