Background and Objectives:Thyroid disease largely affects young females, but the incidence is also
increasing among males. In an effort to avoid the scarring of the neck that
is synonymous with conventional thyroidectomy, endoscopic techniques have
been developed over the years. The transoral endoscopic approach is the
latest of these innovations that promises a scarless surgical outcome. This
review evaluates whether this technique is safe and feasible in live
patients and outlines the outcomes in published literature so far.Database:PubMed, Medline, BioMed Central, Cochrane Library, OVID and Web of Science
were systematically searched by using a Medical Subject Heading
(MeSH)–optimized search strategy. The selection of papers followed
the Preferred Reporting Items for Systematic Reviews and Meta-Analyses
(PRISMA) guidelines after setting strict inclusion and exclusion criteria.
Sixteen studies were included in the final analysis.Discussion:This systematic review presents cases of 785 patients. Surgeons in 15 of the
studies used a completely vestibular approach, whereas those in the
remaining 2 used the floor of the mouth for primary access. Conversion to
open surgery took place in 1.3%. In total, 4.3% of patients
experienced transient laryngeal nerve palsy, whereas 0.1% had
permanent recurrent incidences of the condition. Transient hypocalcemia
occurred in 7.4% of cases, with no recorded permanent cases. Carbon
dioxide embolism occurred in 0.6% of cases, and another 0.6%
had a deep-seated neck infection. The complication rates within the review
were deemed acceptable and the overall technique feasible. A prospective
randomized controlled trial was proposed to compare this technique with
conventional thyroidectomy.