Trans-palpebral illumination: an approach for wide-angle fundus photography without the need for pupil dilation

Toslak, Devrim; Thapa, Damber; Chen, Yanjun; Erol, Muhammet Kazım; Chan, Robison Vernon Paul; Yao, Xincheng

doi:10.1364/ol.41.002688

Cited by 41 publications

(41 citation statements)

References 20 publications

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“…We recently demonstrated trans-palpebral illumination for wide-angle fundus photography 13 . Using a fiber illuminator contacting the eyelid, the trans-palpebral illumination excluded the possibility of eyeball inflammation, contamination, and abrasion associated with trans-scleral illumination.…”

Section: Introductionmentioning

confidence: 99%

“…Using a fiber illuminator contacting the eyelid, the trans-palpebral illumination excluded the possibility of eyeball inflammation, contamination, and abrasion associated with trans-scleral illumination. Without the need for pharmacologic pupil dilation, we have demonstrated nonmydriatic wide field fundus photography using a smartphone-based prototype 13 . However, contact-free imaging is desirable for easy-to-use clinical deployments.…”

Section: Introductionmentioning

confidence: 99%

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Contact-free trans-pars-planar illumination enables snapshot fundus camera for nonmydriatic wide field photography

Wang

Toslak

Alam

et al. 2018

Sci Rep

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In conventional fundus photography, trans-pupillary illumination delivers illuminating light to the interior of the eye through the peripheral area of the pupil, and only the central part of the pupil can be used for collecting imaging light. Therefore, the field of view of conventional fundus cameras is limited, and pupil dilation is required for evaluating the retinal periphery which is frequently affected by diabetic retinopathy (DR), retinopathy of prematurity (ROP), and other chorioretinal conditions. We report here a nonmydriatic wide field fundus camera employing trans-pars-planar illumination which delivers illuminating light through the pars plana, an area outside of the pupil. Trans-pars-planar illumination frees the entire pupil for imaging purpose only, and thus wide field fundus photography can be readily achieved with less pupil dilation. For proof-of-concept testing, using all off-the-shelf components a prototype instrument that can achieve 90° fundus view coverage in single-shot fundus images, without the need of pharmacologic pupil dilation was demonstrated.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Contact-free trans-pars-planar illumination enables snapshot fundus camera for nonmydriatic wide field photography

Wang

Toslak

Alam

et al. 2018

Sci Rep

Self Cite

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“…Therefore, the merged images provide approximately 100° wide-field fundus image, where fundus image is illustrated in [34]. Tolsak et al [31] propose to overlay lenses in order to capture several images in a single-shot image. Thereafter, the images were merged to provide a 152° view.…”

Section: Field Of View (Fov) Of Smartphone Capture Devicesmentioning

confidence: 99%

Detection of retinal abnormalities using smartphone-captured fundus images: a survey

Akil

Elloumi

2019

Real-Time Image Processing and Deep Learning 2019

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Several retinal pathologies lead to severe damages that may achieve vision lost. Moreover, some damages require expensive treatment, other ones are irreversible due to the lack of therapies. Therefore, early diagnoses are highly recommended to control ocular diseases. However, early stages of several ocular pathologies lead to the symptoms that cannot be distinguish by the patients. Moreover, ageing population is an important prevalence factor of ocular diseases which is the cases of most industrial counties. Further, this feature involves a lake of mobility which presents a limiting factor to perform periodical eye screening. Those constraints lead to a late of ocular diagnosis and hence important ocular pathology patients are registered. The forecast statistics indicates that affected population will be increased in coming years. Several devices allowing the capture of the retina have recently been proposed. They are composed by optical lenses which can be snapped on Smartphone, providing fundus images with acceptable quality. Thence, the challenge is to perform automatic ocular pathology detection on Smartphone captured fundus images that achieves higher performance detection while respecting timing constraint with respect to the clinical employment. This paper presents a survey of the Smartphonecaptured fundus image quality and the existing methods that use them for retinal structures and abnormalities detection. For this purpose, we first summarize the works that evaluate the Smartphone-captures fundus image quality and their FOV (field-of-view). Then, we report the capability to detect abnormalities and ocular pathologies from those fundus images. Thereafter, we propose a flowchart of processing pipeline of detecting methods from Smartphone captured fundus images and we investigate about the implementation environment required to perform the detection of retinal abnormalities.

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“…In this study, we developed a new technique by delivering light through the upper eyelid (palpebra) for wide angle fundus photography [11]. This novel trans-palpebral illumination approach enables wide-angle fundus photography without eyeball contact and pupil dilation.…”

Section: Introductionmentioning

confidence: 99%

Wide-field fundus imaging with trans-palpebral illumination

et al. 2017

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In conventional fundus imaging devices, transpupillary illumination is used for illuminating the inside of the eye. In this method, the illumination light is directed into the posterior segment of the eye through the cornea and passes the pupillary area. As a result of sharing the pupillary area for the illumination beam and observation path, pupil dilation is typically necessary for wide-angle fundus examination, and the field of view is inherently limited. An alternative approach is to deliver light from the sclera. It is possible to image a wider retinal area with transcleral-illumination. However, the requirement of physical contact between the illumination probe and the sclera is a drawback of this method. We report here trans-palpebral illumination as a new method to deliver the light through the upper eyelid (palpebra). For this study, we used a 1.5 mm diameter fiber with a warm white LED light source. To illuminate the inside of the eye, the fiber illuminator was placed at the location corresponding to the pars plana region. A custom designed optical system was attached to a digital camera for retinal imaging. The optical system contained a 90 diopter ophthalmic lens and a 25 diopter relay lens. The ophthalmic lens collected light coming from the posterior of the eye and formed an aerial image between the ophthalmic and relay lenses. The aerial image was captured by the camera through the relay lens. An adequate illumination level was obtained to capture wide angle fundus images within ocular safety limits, defined by the ISO 15004-2: 2007 standard. This novel trans-palpebral illumination approach enables wide-angle fundus photography without eyeball contact and pupil dilation.

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Trans-palpebral illumination: an approach for wide-angle fundus photography without the need for pupil dilation

Cited by 41 publications

References 20 publications

Contact-free trans-pars-planar illumination enables snapshot fundus camera for nonmydriatic wide field photography

Contact-free trans-pars-planar illumination enables snapshot fundus camera for nonmydriatic wide field photography

Detection of retinal abnormalities using smartphone-captured fundus images: a survey

Wide-field fundus imaging with trans-palpebral illumination

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