Transapical beating-heart chordae implantation in mitral regurgitation: a new horizon for repairing mitral valve prolapse

Lancellotti, Patrizio; Radermecker, Marc; Durieux, Rodolphe; Modine, Thomas; Oury, Cécile; Fattouch, Khalil

doi:10.21037/jtd.2016.12.78

Cited by 11 publications

(19 citation statements)

References 26 publications

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“…While transapical implantation of neochordae shows promising clinical results [13,14], it requires additional experience and further studies. Some aspects of this technique, such as exact positioning of the neochordae to the prolapsing segment or the length adjustment of the neochordae to eliminate prolapse while preventing additional restriction of the leaflet, can only be assumed at this moment [15].…”

Section: Introductionmentioning

confidence: 99%

Numerical simulation of transapical off-pump mitral valve repair with neochordae implantation

Gaidulis

Votta

Selmi

et al. 2018

THC

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Section: Introductionmentioning

confidence: 99%

Numerical simulation of transapical off-pump mitral valve repair with neochordae implantation

Gaidulis

Votta

Selmi

et al. 2018

THC

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“…Another novel technology for transapical mitral repair is the Harpoon Mitral Valve Repair System (H-MVRS; Harpoon Medical Inc., Baltimore, Maryland, USA). It uses a similar approach to the NeoChord system; however, the mechanism of ePTFE chordae anchoring is different: the device perforates the leaflet and anchors the artificial chord by a self-tying suture knot [1,11]. According to 2019 data, there were 65 patients who underwent this procedure, and it was successful in 62 (95.4%) patients.…”

Section: Discussionmentioning

confidence: 99%

“…Degenerative mitral valve (MV) disease is a common cause of primary mitral regurgitation (MR) in developed countries [1]. Reconstructive MV surgery has become an established gold standard treatment for this condition.…”

Section: Introductionmentioning

confidence: 99%

Comparison of early postoperative results between conventional and transapical mitral valve repair

Zorinas¹,

Lipnevičius²,

Bleizgytė³

et al. 2019

pwki

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Introduction: Conventional mitral valve repair (CMVR) is well-established, safe and effective treatment for degenerative mitral regurgitation (MR). Transapical off-pump implantation of artificial chordae (TA) has been introduced into practice and gained interest among surgeons. However, there are no publications comparing the results between TA and CMVR. Aim: To compare early postoperative outcomes of CMVR with TA in patients with degenerative MR. Material and methods: This was a retrospective cohort study. A total of 169 patients who underwent mitral valve repair between 2011 and 2018 were included in this analysis. Patients were divided into two groups: the TA group, n = 78 and CMVR group, n = 91. The groups were compared for early postoperative outcomes. Results: Patients in the TA group were younger, 54.2 ±11.1 vs. 59.5 ±12.8 years (p = 0.005). Patients in the CMVR group had more complicated postoperative course with higher incidence of blood transfusion (42.9% vs. 7.8%, p = 0.001), atrial fibrillation (25.3% vs. 11.7%, p = 0.031), renal insufficiency (15.4% vs. 2.6%, p = 0.007) and stroke (2.1% vs. 0%). In the early postoperative period, one patient died in the TA group, and there were no deaths in the CMVR group (p = 0.277). Residual moderate to severe mitral regurgitation was present in nine (11.5%) TA patients, while none of the patients in the CMVR group had moderate or a higher degree of residual regurgitation (p = 0.001). Conclusions: Off-pump transapical MV repair is a feasible and safe procedure with low postoperative morbidity rates. Higher rates of mitral regurgitation reoccurrence would require a careful and thorough selection of the patients suitable for the TA approach.

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“…While transapical implantation of neochordae shows promising clinical results (Rucinskas et al 2014;Lancellotti et al 2016;Colli et al 2016;Colli et al 2018;Kiefer et al 2018), there are some problematic aspects regarding this surgical technique. The main challenge that emerges in case of transapical MV repair is the correct length adjustment of the neochordae.…”

Section: Modeling Strategy For Transapical Mitral Valve Repair Simulamentioning

confidence: 99%

Numerical modeling of transapical mitral valve repair

Gaidulis¹

2019

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Transapical beating-heart chordae implantation in mitral regurgitation: a new horizon for repairing mitral valve prolapse

Cited by 11 publications

References 26 publications

Numerical simulation of transapical off-pump mitral valve repair with neochordae implantation

Numerical simulation of transapical off-pump mitral valve repair with neochordae implantation

Comparison of early postoperative results between conventional and transapical mitral valve repair

Numerical modeling of transapical mitral valve repair

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