2008
DOI: 10.1016/j.athoracsur.2008.05.039
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Transapical Mitral Valved Stent Implantation

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Cited by 37 publications
(21 citation statements)
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“…[32][33][34][35][36][37][38][39] During first studies, 30 pigs underwent off-pump mitral valved stent implantation with followup times of 60 minutes and 7 days. Accurate positioning was established in all but 5 animals.…”
Section: Preclinical Developmentmentioning
confidence: 99%
“…[32][33][34][35][36][37][38][39] During first studies, 30 pigs underwent off-pump mitral valved stent implantation with followup times of 60 minutes and 7 days. Accurate positioning was established in all but 5 animals.…”
Section: Preclinical Developmentmentioning
confidence: 99%
“…However, due to the complex anatomic structure of the mitral valve apparatus and the absence of a reliable 'landing zone' [10] , most results are from animal experiments only [7] . VIV and VIR implantation techniques into the mitral position haven been clinically introduced more successfully.…”
Section: Discussionmentioning
confidence: 99%
“…Transfemoral and transapical transcatheter aortic valve implantation (TAVI) have shown very promising clinical results in selected patient populations. Although transcatheter mitral valve replacement has mostly remained at the stage of animal evaluation [7,8] , transcatheter mitral valve-invalve (VIV) or valve-in-ring (VIR) implantation has slowly entered clinical practice. The VIR technique turns out to be a potential therapeutic technique for high-risk patients with mitral repair failure.…”
Section: Introductionmentioning
confidence: 99%
“…Seven of the 8 animals died as a result of paravalvular leaks, suboptimal positioning, or failure of fixation. 69 A subsequent bovine pericardial design with a unique ventricular tethering fixation system reduced embolization, and all animals with initially successful implants maintained normal hemodynamics and stability to 8 weeks. 70 Initial first-in-human temporary implants during surgical mitral valve replacement were performed in 2013.…”
Section: Fortismentioning
confidence: 99%
“…All patients were considered extreme risk for surgery, and 3 of the 4 died within 3 months post procedure. 69 This group published their initial experience with a transapical, off-pump, porcine self-expanding stent prosthesis in pigs. Seven of the 8 animals died as a result of paravalvular leaks, suboptimal positioning, or failure of fixation.…”
Section: Fortismentioning
confidence: 99%