Transatlantic Editorial on Transcatheter Aortic Valve Replacement

Thourani, Vinod H.; Borger, Michael A.; Holmes, David R.; Maniar, Hersh S.; Pinto, Fausto J.; Miller, Craig; Rodés‐Cabau, Josep; Mohr, Friedrich W.; Schröfel, Holger; Moat, Neil; Beyersdorf, Friedhelm; Patterson, G. Alexander; Weisel, Richard D.

doi:10.1016/j.athoracsur.2017.04.030

Cited by 4 publications

(1 citation statement)

References 90 publications

(126 reference statements)

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“…For example, in heart failure patients, major differences were observed in discharge strategies with shorter length of stay in North America 8 9. Transatlantic variation has to some extent been outlined for transcatheter aortic valve replacement patients10; however, literature on differences in perioperative care or outcomes for SAVR patients is still lacking.…”

Section: Discussionmentioning

confidence: 99%

Perioperative care differences of surgical aortic valve replacement between North America and Europe

Velders

Vriesendorp

Rao

et al. 2023

Heart

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ObjectiveTo describe differences between North America and Europe in the perioperative management of patients undergoing surgical aortic valve replacement (SAVR).MethodsPatients with moderate or greater aortic stenosis or regurgitation requiring SAVR were enrolled in a prospective observational cohort evaluating the safety and efficacy of a new stented bioprosthesis at 25 centres in North America (Canada and the USA) and 13 centres in Europe (Germany, the Netherlands, France, the UK, Switzerland and Italy). While all patients underwent implantation with the same bioprosthetic model, perioperative management was left to the discretion of participating centres. Perioperative care was described in detail including outcomes up to 1-year follow-up.ResultsAmong 1118 patients, 643 (58%) were implanted in North America, and 475 (42%) were implanted in Europe. Patients in Europe were older, had a lower body mass index, less bicuspid disease and worse degree of aortic stenosis at baseline. In Europe, anticoagulant therapy at discharge was more aggressive, whereas length of stay was longer, and discharges directly to home were less common. Rehospitalisation risk was lower in Europe at 30 days (8.5% vs 15.9%) but converged at 1-year follow-up (26.5% vs 28.1%). Within continents, there were major differences between individual countries concerning perioperative management.ConclusionContemporary perioperative management of SAVR patients varies between North America and Europe in patient selection, procedural techniques, antithrombotic regimen and discharge management. Furthermore, rehospitalisation differed largely between continents and countries. Hence, geographical setting must be considered during design and interpretation of trials on SAVR.Trial registration numberNCT02088554.

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Section: Discussionmentioning

confidence: 99%