2004
DOI: 10.1016/j.ijpharm.2004.01.041
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Transbuccal permeation, anti-inflammatory activity and clinical efficacy of piroxicam formulated in different gels

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Cited by 57 publications
(22 citation statements)
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“…Attia et al 27) have used a group of cellulosic polymers such as HPMC, HPC, HEC and/or non-cellulosic based gel forming polymers like PVA, carbapol, pluronic and Na alginate to provide bioadhesiveness for piroxicam buccal gel. The obtained results showed that 7% Na alginate, 2.5% HPMC and 3% MC were good mucoadhesive agents that enhanced the membrane oral permeability of the drug.…”
Section: )mentioning
confidence: 99%
“…Attia et al 27) have used a group of cellulosic polymers such as HPMC, HPC, HEC and/or non-cellulosic based gel forming polymers like PVA, carbapol, pluronic and Na alginate to provide bioadhesiveness for piroxicam buccal gel. The obtained results showed that 7% Na alginate, 2.5% HPMC and 3% MC were good mucoadhesive agents that enhanced the membrane oral permeability of the drug.…”
Section: )mentioning
confidence: 99%
“…The receiver chambers of these diffusion cells are typically maintained at 37°C while the donor chamber is kept at ambient temperature, typically 22-24°C (31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42)(43). Such an experimental setup for in vitro permeation studies across the buccal mucosa does not mimic the in vivo condition.…”
Section: Introductionmentioning
confidence: 99%
“…The obtained buccal mucosa membrane was mounted between the donor and receiver compartments of the Franztype diffusion cell, with the epithelial side facing the donor compartment to allow contact with the film (Attia et al, 2004). The receiver chamber was filled with 8mL of SS at 37°C and uniform mixing was provided by magnetic stirring at 250 rev/min.…”
mentioning
confidence: 99%