“…Aortic regurgitation was reported in 1028 patients in thirteen studies with a weighted mean of 14.46 12.56% [ 16 , 19 , 20 , 22 , 23 , 24 , 25 , 28 , 29 , 31 , 32 , 33 , 34 ]. The presence of a bicuspid valve was reported in seven studies involving 860 out of 9855 patients with a weighted mean of 8.72 12.87% [ 8 , 17 , 18 , 21 , 26 , 27 , 30 ]. Left ventricular ejection fraction was reported in sixteen studies, and the weighted mean left ventricular ejection fraction was 60.46 4.36% [ 8 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 25 , 26 , 28 , 30 , 31 , 32 , 33 , 34 ].…”