Transcatheter and surgical treatment of tricuspid regurgitation: Predicting right ventricular decompensation and favorable responders

Sala, Alessandra; Beneduce, Alessandro

doi:10.3389/fcvm.2022.980639

Cited by 8 publications

(3 citation statements)

References 55 publications

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“…31 The degree of RV dysfunction has prognostic implications for patients with TR. 32 The key predictors of adverse post-TV intervention were found to be the RV itself and elevated pulmonary pressures.…”

Section: Rv Function and Echocardiographymentioning

confidence: 98%

The Tricuspid Valve: A Review of Pathology, Imaging, and Current Treatment Options: A Scientific Statement From the American Heart Association

Davidson,

Tang,

et al. 2024

Circulation

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Tricuspid valve disease is an often underrecognized clinical problem that is associated with significant morbidity and mortality. Unfortunately, patients will often present late in their disease course with severe right-sided heart failure, pulmonary hypertension, and life-limiting symptoms that have few durable treatment options. Traditionally, the only treatment for tricuspid valve disease has been medical therapy or surgery; however, there have been increasing interest and success with the use of transcatheter tricuspid valve therapies over the past several years to treat patients with previously limited therapeutic options. The tricuspid valve is complex anatomically, lying adjacent to important anatomic structures such as the right coronary artery and the atrioventricular node, and is the passageway for permanent pacemaker leads into the right ventricle. In addition, the mechanism of tricuspid pathology varies widely between patients, which can be due to primary, secondary, or a combination of causes, meaning that it is not possible for 1 type of device to be suitable for treatment of all cases of tricuspid valve disease. To best visualize the pathology, several modalities of advanced cardiac imaging are often required, including transthoracic echocardiography, transesophageal echocardiography, cardiac computed tomography, and cardiac magnetic resonance imaging, to best visualize the pathology. This detailed imaging provides important information for choosing the ideal transcatheter treatment options for patients with tricuspid valve disease, taking into account the need for the lifetime management of the patient. This review highlights the important background, anatomic considerations, therapeutic options, and future directions with regard to treatment of tricuspid valve disease.

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Section: Rv Function and Echocardiographymentioning

confidence: 98%

The Tricuspid Valve: A Review of Pathology, Imaging, and Current Treatment Options: A Scientific Statement From the American Heart Association

Davidson,

Tang,

et al. 2024

Circulation

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“…Identifying predictors of outcomes and discriminating patients who are responders or non-responders to TR intervention is of paramount importance in guiding the decision-making process for TR surgical management [ 23 ].…”

Section: Tr Surgical Indicationmentioning

confidence: 99%

Present and Future Surgical Options for Tricuspid Regurgitation

Tagliari,

Taramasso

2024

Rev. Cardiovasc. Med.

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Tricuspid regurgitation, once considered a relatively benign condition, has now gathered significant attention due to new evidence showing its impact on both short- and long-term follow-up. While surgical intervention remains the established standard approach for treating severe tricuspid regurgitation, current guidelines provide Class I indication for intervention in only a limited set of scenarios. This review delves into the present and future perspectives of surgical tricuspid regurgitation management, examining aspects such as disease prognosis, surgical indications, outcomes, and a comprehensive overview of past and upcoming clinical trials.

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“… 94 Nonetheless, moderate or more (≥2+) residual TR following device therapy is associated with adverse outcomes. 39 , 95 Given the pitfalls of postdevice quantitative methods depending on device type, 3D-VCA may be an important method for assessing both baseline and postdevice efficacy; however, significant limitations of this method also exist. Precise algorithms to integrate discordant parameters need to be developed and validated.…”

Section: Section 2: Endpoint Definitionsmentioning

confidence: 99%

Tricuspid Valve Academic Research Consortium Definitions for Tricuspid Regurgitation and Trial Endpoints

Hahn,

Lawlor,

Davidson

et al. 2023

European Heart Journal

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Interest in the pathophysiology, etiology, management, and outcomes of patients with tricuspid regurgitation (TR) has grown in the wake of multiple natural history studies showing progressively worse outcomes associated with increasing TR severity, even after adjusting for multiple comorbidities. Historically, isolated tricuspid valve surgery has been associated with high in-hospital mortality rates, leading to the development of transcatheter treatment options. The aim of this first Tricuspid Valve Academic Research Consortium document is to standardize definitions of disease etiology and severity, as well as endpoints for trials that aim to address the gaps in our knowledge related to identification and management of patients with TR. Standardizing endpoints for trials should provide consistency and enable meaningful comparisons between clinical trials. A second Tricuspid Valve Academic Research Consortium document will focus on further defining trial endpoints and will discuss trial design options.

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Transcatheter and surgical treatment of tricuspid regurgitation: Predicting right ventricular decompensation and favorable responders

Cited by 8 publications

References 55 publications

The Tricuspid Valve: A Review of Pathology, Imaging, and Current Treatment Options: A Scientific Statement From the American Heart Association

The Tricuspid Valve: A Review of Pathology, Imaging, and Current Treatment Options: A Scientific Statement From the American Heart Association

Present and Future Surgical Options for Tricuspid Regurgitation

Tricuspid Valve Academic Research Consortium Definitions for Tricuspid Regurgitation and Trial Endpoints

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