2015
DOI: 10.1002/ccd.26253
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Transcatheter aortic valve implantation for paradoxical low‐flow low‐gradient aortic stenosis patients

Abstract: As opposed to LEF-LG patients, mid-term prognosis after TAVI procedure in PLFLG patients is similar to HGAS patients despite higher perioperative mortality.

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Cited by 31 publications
(18 citation statements)
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“…In this issue of Catheterization Cardiovascular Interventions , Debry et al compare the short‐ and mid‐term clinical outcomes of patients that underwent transcatheter aortic valve replacement (TAVR) by classifying AS patients into three groups: PLFLG, low flow ejection fraction low gradient (LEFLG), and HGAS. Their report supports existing evidence that PLFLG AS is commonly seen in older, female patients with a history of hypertension . Thus, PLFLG AS patients have a greater arterial afterload than patients with HGAS .…”
supporting
confidence: 80%
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“…In this issue of Catheterization Cardiovascular Interventions , Debry et al compare the short‐ and mid‐term clinical outcomes of patients that underwent transcatheter aortic valve replacement (TAVR) by classifying AS patients into three groups: PLFLG, low flow ejection fraction low gradient (LEFLG), and HGAS. Their report supports existing evidence that PLFLG AS is commonly seen in older, female patients with a history of hypertension . Thus, PLFLG AS patients have a greater arterial afterload than patients with HGAS .…”
supporting
confidence: 80%
“…Their report supports existing evidence that PLFLG AS is commonly seen in older, female patients with a history of hypertension . Thus, PLFLG AS patients have a greater arterial afterload than patients with HGAS . Their findings also support that TAVR is a feasible treatment strategy for these patients with comparable mid‐term survival to TAVR in HGAS patients .…”
supporting
confidence: 75%
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“…Likewise, in the UK-TAVI registry, abnormal LVEF (<50%) was associated with an increased mortality at 2-year follow-up after TAVI only in patients with low-gradient AS (defined as a peak transvalvular aortic gradient <64 mm Hg), while in the subgroup of patients with normal LVEF, there was no difference in 2-year mortality after TAVI in patients with LGAS and those with high gradients 3. In the minority of patients with both moderately/severely abnormal LVEF and LGAS (83 of 624[13.3%] patients in this study and 8.4%-22.5% in other studies with variable definition of an abnormal LVEF3,4,26,28 ), TAVI may still be considered given the fact that 1-year mortality after TAVI, although high, is lower when compared to patients with medical management only 8. Both impaired LVEF and LGAS were associated with greater 1-year mortality in univariate analysis.…”
contrasting
confidence: 50%