Transcatheter aortic valve implantation in patients with and without concomitant coronary artery disease: comparison of characteristics and early outcome in the German multicenter TAVI registry

Comparison of dual antiplatelet therapy versus oral anticoagulation following transcatheter aortic valve replacement: A retrospective single-center registry analysis

“…In the present study, the incidence of all-cause mortality, stroke and MI at 30 days was comparable to results previously published in prospective landmark trials as well as nationwide registries [16][17][18][19][20]. Post interventional DAPT or OAC resulted in similar rates of MI, stroke and all-cause mortality up to 6 months after TAVR thereby underscoring the efficacy of both therapeutic regimens.…”

Diagnostic accuracy of computed tomography angiography for the detection of coronary artery disease in patients referred for transcatheter aortic valve implantation

“…The pre-procedural assessment of CAD is required to determine both the baseline risk characteristics and the Table 4 Diagnostic accuracy of computed tomography as compared with invasive coronary angiography in patients after coronary artery bypass grafting in a segment-based analysis need for coronary revascularization in the TAVI population [4]. Currently, ICA remains the gold standard for the identification of CAD before TAVI; however, it still carries a non-negligible risk for contrast-induced nephropathy that should be of special concern in the frail TAVI population [13,14].…”

“…In the diagnostic work-up of patients evaluated for TAVI, a pre-procedural assessment of coronary artery disease (CAD) is mandatory to determine both the baseline risk characteristics and the need for coronary revascularization [4]. Currently, invasive coronary angiography (ICA) remains the gold standard diagnostic modality for the detection of significant CAD in patients scheduled for TAVI; however, it still carries a non-negligible risk for catheter-related complications as well as increased contrast dye use, both of which should be of special concern in the frail TAVI population.…”

The percutaneous coronary intervention prior to transcatheter aortic valve implantation (ACTIVATION) trial: study protocol for a randomized controlled trial

“…These patients had a greater in-hospital mortality (10.0 versus 5.5%, P <0.01), required more frequent cardio-pulmonary resuscitation (7.8 versus 3.5%, P <0.01) and suffered greater 30-day mortality (log rank P  = 0.041). But there were significant differences in the group demographics: more frequent peripheral vascular disease, lower left ventricular (LV) ejection fraction and higher logistic EuroScores in patients with CAD [23]. The Italian CoreValve registry noted that in patients with critical ostial disease, myocardial infarction (MI) within 12 months of TAVI was greater in those patients who were not revascularized prior to TAVI [24].…”