2020
DOI: 10.21037/atm.2020.03.155
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Transcatheter aortic valve replacement (TAVR): expanding indications to low-risk patients

Abstract: Aortic stenosis (AS) is the most common cardiac valve disease in developed countries.Transcatheter aortic valve replacement (TAVR) for the treatment of severe symptomatic AS is an accepted therapy option for elderly patients with symptomatic severe AS. Nowadays, TAVR has revolutionized the treatment of AS with an exponential growth worldwide. Both the development of new generation valves and the experience of the operating teams have contributed significantly to decrease the complications rate after TAVR. Seve… Show more

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Cited by 5 publications
(4 citation statements)
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“…Further research should be conducted to individualize perioperative management to identify situations in which emergency TAVI benefits more and situations in which expanded use of BAV is warranted. Nowadays, the indications of TAVI are expanding [ 22 ] and TAVI is growing rapidly worldwide [ 23 ]. This may lead to longer wait times for TAVI patients to undergo surgery and greater risk for interval decompensation [ 6 ].…”
Section: Discussionmentioning
confidence: 99%
“…Further research should be conducted to individualize perioperative management to identify situations in which emergency TAVI benefits more and situations in which expanded use of BAV is warranted. Nowadays, the indications of TAVI are expanding [ 22 ] and TAVI is growing rapidly worldwide [ 23 ]. This may lead to longer wait times for TAVI patients to undergo surgery and greater risk for interval decompensation [ 6 ].…”
Section: Discussionmentioning
confidence: 99%
“…Introduced in 2002 (1), transcatheter aortic valve replacement (TAVR) has since become an effective alternative to surgical aortic valve replacement in lowto-high-risk patients with symptomatic aortic stenosis (2)(3)(4)(5)(6). The two commercially available design categories of transcatheter heart valves (THV), namely balloonexpandable valves (BEV) and self-expanding valves (SEV), each have their own advantages and disadvantages.…”
Section: Introductionmentioning
confidence: 99%
“…Over the past decade, better clinical outcomes have been achieved because of transcatheter heart valve (THV) design improvements, optimized preprocedural planning, as well as increased operator experience 8–10 . However, post‐TAVR new‐onset conduction disturbances and permanent pacemaker implantation (PPMI) remain common procedural complications, especially in TAVR using self‐expanding THVs 11–13 …”
Section: Introductionmentioning
confidence: 99%
“…[8][9][10] However, post-TAVR new-onset conduction disturbances and permanent pacemaker implantation (PPMI) remain common procedural complications, especially in TAVR using self-expanding THVs. [11][12][13] Previous studies have reported various factors impacting the risk of post-TAVR PPMI, including preprocedural factors such as preexisting conduction abnormalities, membranous septum length, and aortic root calcium distribution, as well as procedural factors such as the choice of THV type, degree of THV oversizing, and implantation depth. 14 To implant self-expanding THVs, different implantation techniques have been used over the past few years.…”
Section: Introductionmentioning
confidence: 99%