Transcatheter device closure of perimembranous ventricular septal defect in pediatric patients: Long-term outcomes

Shah, Jay; Saraiya, Sanket Pravinchandra; Nikam, Tushar; Jha, Mukesh Jitendra

doi:10.4103/heartviews.heartviews_13_19

Cited by 15 publications

(19 citation statements)

References 40 publications

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“…There is no doubt that surgical repair has better extensive indications and high success rate [ 5 , 6 ]. Compared with traditional open chest repair, the most obvious advantage of minimally invasive transcatheter closure is the avoidance of Cardiopulmonary bypass (CPB), CPB-related complications, especially those related to brain damage, which have been widely reported [ 7 , 8 ]; and the incidence of arrhythmia after minimally invasive transcatheter closure is lower than the former [ 9 – 11 ]. There are two kinds of minimally invasive closure of VSD, TTCVSD and PTCVSD.…”

Section: Discussionmentioning

confidence: 99%

Comparison of the clinical effect between the lower sternal incision and the left parasternal fourth intercostal incision in the transthoracic closure of ventricular septal defect

Shangguan

Liao

2021

J Cardiothorac Surg

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Background To analyze the clinical effect of two different ways of minimally invasive transthoracic closure in children with ventricular septal defect (VSD). Methods From January 2015 to July 2019, 294 children with VSD were enrolled in the Fujian Medical University Union Hospital. Patients were divided into two groups – those who underwent VSD closure through the left sternal fourth intercostal incision (group A: n = 95) and the lower sternal incision (group B: n = 129). Results The operation time, bleeding volume, postoperative mechanical ventilation time, postoperative intensive care unit (ICU) monitoring time, postoperative hospitalization time and complication rate in group A were significantly lower than those in group B (P < 0.05). There was no significant difference between the two groups in the operation success rate, mechanical ventilation time and total hospitalization cost (P > 0.05). Conclusion The transthoracic closure of ventricular septal defect through the left sternal fourth intercostal incision is feasible, safe, cosmetic, and worth popularizing.

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Section: Discussionmentioning

confidence: 99%

Comparison of the clinical effect between the lower sternal incision and the left parasternal fourth intercostal incision in the transthoracic closure of ventricular septal defect

Shangguan

Liao

2021

J Cardiothorac Surg

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“…In fact, the proximity of the margins of pmVSD to the conduction system and aortic valves increases the risk of adverse events related to percutaneous closure, leading to several complications. 30 Our study included 37 mVSD, 437 pmVSD, and a single hybrid VSD. The results showed that using the ADO II for VSD closure has a very high success rate and a relatively low incidence of complications.…”

Section: Es (95% Ci)mentioning

confidence: 99%

“…18 In the follow -up of other conventional blockers, the occurrence of RSs was found to be much lower than that observed immediately after the device was closed, indicating that time is critical for small RS closure. 29,30,32,33 The population of the ADO II study in this meta -analysis included all patients with defects less than 6.5 mm, small VSD shunt volumes, and smaller RSs after surgery, and some of them closed spontaneously during follow -up.…”

Section: Es (95% Ci)mentioning

confidence: 99%

“…Due to the low probability of new valve regurgitation after the surgery, the stable hemodynamic state in the cardiac cavity is more conducive to endothelialization and endocardial formation, so even if a small amount of RS occurs, it can spontaneously disappear after a few weeks or months. 29,30,32,33 complete atrioventricular block Complete atrioventricular block is a major challenge for transcatheter closure of pmVSD. 11 It can occur during surgery or months and years afterward.…”

Section: Es (95% Ci)mentioning

confidence: 99%

“…11 It can occur during surgery or months and years afterward. 30 It may be reversible or persistent, and persistent cAVB requires permanent pacing. Although the mechanism of cAVB is unknown, possible causes are as follows.…”

Section: Es (95% Ci)mentioning

confidence: 99%

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Efficacy and safety of the Amplatzer Duct Occluder II for ventricular septal defect closure: a meta-analysis

Cen¹,

Peng²,

Li³

et al. 2021

Kardiol Pol

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Background Transcatheter closure has become an effective and safe method to repair ventricular septal defects (VSDs). However, the devices used for VSD closure in the past frequently led to serious complications, such as complete atrioventricular block. The second -generation device, the Amplatzer Duct Occluder (ADO II), was originally designed to block small-and medium -sized patent ductus arteriosus. Interestingly, there are some reports of the use of the ADO II to close VSD because of less complications. aims A meta -analysis of the literature was performed to systematically investigate the efficacy and safety of the ADO II for VSD closure. methods The Embase, PubMed, Cochrane, and Web of Science databases were searched for original studies on VSD closure with the ADO II up to March 15, 2020. The random -effects model and summary rate were employed to estimate the success and complications of VSD closure with the ADO II. results A total of 13 articles comprising 478 patients with VSD were included. The age of the patients ranged from 0.5 to 55.7 years. The overall estimated device -implantation success rate was 99% (95% CI, 98%-100%). Residual shunts (pooled rate, 4%; 95% CI, 1%-7%) and postoperative aortic valve regurgitation (pooled rate, 0%; 95% CI, 0-1%) were common complications. Only 3 patients developed device embolism. conclusions The ADO II may be a safer and more effective transcatheter closure device for patients with VSD due to its higher success rate and lower complication rate, as compared with other devices.

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Progress of biodegradable polymer application in cardiac occluders

Xu,

Fa,

Yang

et al. 2023

J Biomed Mater Res

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Cardiac septal defect is the most prevalent congenital heart disease and is typically treated with open‐heart surgery under cardiopulmonary bypass. Since the 1990s, with the advancement of interventional techniques and minimally invasive transthoracic closure techniques, cardiac occluder implantation represented by the Amplazter products has been the preferred treatment option. Currently, most occlusion devices used in clinical settings are primarily composed of Nitinol as the skeleton. Nevertheless, long‐term follow‐up studies have revealed various complications related to metal skeletons, including hemolysis, thrombus, metal allergy, cardiac erosion, and even severe atrioventricular block. Thus, occlusion devices made of biodegradable materials have become the focus of research. Over the past two decades, several bioabsorbable cardiac occluders for ventricular septal defect and atrial septal defect have been designed and trialed on animals or humans. This review summarizes the research progress of bioabsorbable cardiac occluders, the advantages and disadvantages of different biodegradable polymers used to fabricate occluders, and discusses future research directions concerning the structures and materials of bioabsorbable cardiac occluders.

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Transcatheter device closure of perimembranous ventricular septal defect in pediatric patients: Long-term outcomes

Cited by 15 publications

References 40 publications

Comparison of the clinical effect between the lower sternal incision and the left parasternal fourth intercostal incision in the transthoracic closure of ventricular septal defect

Comparison of the clinical effect between the lower sternal incision and the left parasternal fourth intercostal incision in the transthoracic closure of ventricular septal defect

Efficacy and safety of the Amplatzer Duct Occluder II for ventricular septal defect closure: a meta-analysis

Progress of biodegradable polymer application in cardiac occluders

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