Transcendence of Medicine Regenerative Strategies in the Treatment for Diabetic Foot Ulcers

Abstract

The Diabetes Mellitus type 2 and one of its complications, the diabetic foot ulcer (DFU), are a great problem of public health that affects millions of people around the world. Due to its complexity, DFUs treatment and handling are expensive and complex. In addition, amputations of lower limbs and death are relatively frequent because conventional treatment cannot avoid them. In other hand, the use of growth factors, 3D scaffolds and mesenchymal stem cells, called regenerative medicine (RM), have created new perspectives about the treatment of this kind of injuries. The RM has demonstrated favorable clinical outcomes not only in the case of DFUs, so that, this new medicine area promises to become an important tool that supports or substitutes to conventional treatment in cases of tissue or organic damage caused by the different chronic and traumatic diseases.