While the distribution of the non-trivial zeros of the Riemann zeta function constitutes a central theme in Mathematics, nothing is known about the algebraic nature of these non-trivial zeros. In this article, we study the transcendental nature of sums of the form ρ R(ρ)x ρ , where the sum is over the non-trivial zeros ρ of ζ(s), R(x) ∈ Q(x) is a rational function over algebraic numbers and x > 0 is a real algebraic number. In particular, we show that the function f (x) = ρ x ρ ρhas infinitely many zeros in (1, ∞), at most one of which is algebraic. The transcendence tools required for studying f (x) in the range x < 1 seem to be different from those in the range x > 1. For x < 1, we have the following non-vanishing theorem: If for anwhere χ −d is the quadratic character associated to the imaginary quadratic field K := Q( √ −d). Finally, we consider analogous questions for elements in the Selberg class.Our proofs rest on results from analytic as well as transcendental number theory.