Transcranial Magnetic Stimulation Across the Lifespan: Impact of Developmental and Degenerative Processes

Oberman, Lindsay M.; Benussi, Alberto

doi:10.1016/j.biopsych.2023.07.012

Cited by 7 publications

(4 citation statements)

References 137 publications

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“…The efficacy of TMS in enhancing attention in healthy individuals involves the application of magnetic fields to specific areas of the brain, affecting neural activity [ 19 ]. Several studies have explored the potential of TMS to enhance cognitive functions, including attention, in healthy individuals [ 85 , 86 , 87 ]. The idea is to modulate neural circuits related to attention and executive functions to improve cognitive performance.…”

Section: Clinical Applications: Tms For Adhd and Depressionmentioning

confidence: 99%

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The Use of Transcranial Magnetic Stimulation in Attention Optimization Research: A Review from Basic Theory to Findings in Attention-Deficit/Hyperactivity Disorder and Depression

Yen,

Valentine,

Chiang

2024

Life

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This review explores the pivotal role of attention in everyday life, emphasizing the significance of studying attention-related brain functions. We delve into the development of methodologies for investigating attention and highlight the crucial role of brain neuroimaging and transcranial magnetic stimulation (TMS) in advancing attention research. Attention optimization theory is introduced to elucidate the neural basis of attention, identifying key brain regions and neural circuits involved in attention processes. The theory further explores neuroplasticity, shedding light on how the brain dynamically adapts and changes to optimize attention. A comprehensive overview of TMS is provided, elucidating the principles and applications of this technique in affecting brain activity through magnetic field stimulation. The application of TMS in attention research is discussed, outlining how it can be employed to regulate attention networks. The clinical applications of TMS are explored in attention-deficit/hyperactivity disorder (ADHD) and depression. TMS emerges as an effective clinical treatment for ADHD, showcasing its potential in addressing attention-related disorders. Additionally, the paper emphasizes the efficacy of TMS technology as a method for regulating depression, further underlining the versatility and therapeutic potential of TMS in clinical settings. In conclusion, this review underscores the interdisciplinary approach to attention research, integrating neuroimaging, neuroplasticity, and TMS. The presented findings contribute to our understanding of attention mechanisms and highlight the promising clinical applications of TMS in addressing attention-related disorders. This synthesis of theoretical and practical insights aims to propel further advancements in attention research and its therapeutic applications.

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Section: Clinical Applications: Tms For Adhd and Depressionmentioning

confidence: 99%

“…Several studies have explored the potential of TMS to enhance cognitive functions, including attention, in healthy individuals [85][86][87]. The idea is to modulate neural circuits related to attention and executive functions to improve cognitive performance.…”

Section: Clinical Applications: Tms For Adhd and Depressionmentioning

confidence: 99%

The Use of Transcranial Magnetic Stimulation in Attention Optimization Research: A Review from Basic Theory to Findings in Attention-Deficit/Hyperactivity Disorder and Depression

Yen,

Valentine,

Chiang

2024

Life

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“…Transcranial Magnetic Stimulation (TMS) has increasingly gained attention in the clinical field as a safe and non-invasive method of neural modulation, which has shown significant therapeutic effects in the treatment of depression, anxiety, and other neurological disorders. 6 , 7 This technology is not only widely used in clinical therapy but also in scientific research and clinical diagnosis. It enables real-time assessment of motor areas, corticospinal tracts, and neural pathways in conditions including cognitive impairment and dementia.…”

Section: Introductionmentioning

confidence: 99%

Recent Research Progress on the Use of Transcranial Magnetic Stimulation in the Treatment of Vascular Cognitive Impairment

Li,

Xiao

2024

NDT

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“…As a consequence, there are no universally defined stimulation protocols, and therefore functional outcomes of magnetic brain stimulation are variable between subjects and studies, and underlying molecular mechanisms remain ill defined [3][4][5][6]. Information about these underlying cellular mechanisms is necessary if we aim to identify the most appropriate stimulation protocols for different brain areas; at different life stages (e.g., child, adult, or aged); and in different pathological conditions, e.g., developmental disorder, injury, or neurodegenerative disease [7,8]. Overview of electromagnetic induction in TMS: (A) A brief pulsed current flows through a coil generating a magnetic field, which passes through the skull and induces a secondary current, which stimulates the brain.…”

Section: Introduction: Why Use Magnetic Fields To Stimulate the Brain?mentioning

confidence: 99%

Magnetic Stimulation as a Therapeutic Approach for Brain Modulation and Repair: Underlying Molecular and Cellular Mechanisms

Dufor,

Lohof,

Sherrard

2023

IJMS

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Neurological and psychiatric diseases generally have no cure, so innovative non-pharmacological treatments, including non-invasive brain stimulation, are interesting therapeutic tools as they aim to trigger intrinsic neural repair mechanisms. A common brain stimulation technique involves the application of pulsed magnetic fields to affected brain regions. However, investigations of magnetic brain stimulation are complicated by the use of many different stimulation parameters. Magnetic brain stimulation is usually divided into two poorly connected approaches: (1) clinically used high-intensity stimulation (0.5–2 Tesla, T) and (2) experimental or epidemiologically studied low-intensity stimulation (μT–mT). Human tests of both approaches are reported to have beneficial outcomes, but the underlying biology is unclear, and thus optimal stimulation parameters remain ill defined. Here, we aim to bring together what is known about the biology of magnetic brain stimulation from human, animal, and in vitro studies. We identify the common effects of different stimulation protocols; show how different types of pulsed magnetic fields interact with nervous tissue; and describe cellular mechanisms underlying their effects—from intracellular signalling cascades, through synaptic plasticity and the modulation of network activity, to long-term structural changes in neural circuits. Recent advances in magneto-biology show clear mechanisms that may explain low-intensity stimulation effects in the brain. With its large breadth of stimulation parameters, not available to high-intensity stimulation, low-intensity focal magnetic stimulation becomes a potentially powerful treatment tool for human application.

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Transcranial Magnetic Stimulation Across the Lifespan: Impact of Developmental and Degenerative Processes

Cited by 7 publications

References 137 publications

The Use of Transcranial Magnetic Stimulation in Attention Optimization Research: A Review from Basic Theory to Findings in Attention-Deficit/Hyperactivity Disorder and Depression

The Use of Transcranial Magnetic Stimulation in Attention Optimization Research: A Review from Basic Theory to Findings in Attention-Deficit/Hyperactivity Disorder and Depression

Recent Research Progress on the Use of Transcranial Magnetic Stimulation in the Treatment of Vascular Cognitive Impairment

Magnetic Stimulation as a Therapeutic Approach for Brain Modulation and Repair: Underlying Molecular and Cellular Mechanisms

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