Transcriptional signatures of cortical structural changes in chronic insomnia disorder
Liyong Yu,
Daijie Hu,
Yucai Luo
et al.
Abstract:Chronic insomnia disorder (CID) is a multidimensional disease that may influence various levels of brain organization, spanning the macroscopic structural connectome to microscopic gene expression. However, the connection between genomic variations and morphological alterations in CID remains unclear. Here, we investigated brain structural changes in CID patients at the whole‐brain level and whether these link to transcriptional characteristics. Brain structural data from 104 CID patients and 102 matched healt… Show more
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