“…Although most available data were obtained in rodents and humans, recent studies have shown a single evolutionary origin of the metazoan SC [Fraune et al, 2012b[Fraune et al, , 2013[Fraune et al, , 2014. All 7 mammalian SC components are meiosis-specific [da Cruz et al, 2016] and contain α-helical domains that are predicted to form coiled coils, which are capable of homotypic and heterotypic protein interactions. Moreover, most SC components have been shown to be able to assemble higher order structures [Yuan et al, 1998;Öllinger et al, 2005;Davies et al, 2012;Lu et al, 2014].…”