2023
DOI: 10.7717/peerj.16214
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Transcriptome analysis reveals the mechanism of pyroptosis-related genes in septic cardiomyopathy

Haoyan Zhu,
Jiahe Wu,
Chenze Li
et al.

Abstract: Background Septic cardiomyopathy (SC) is characterized by myocardial dysfunction caused by sepsis and constitutes one of the serious complications of sepsis. Pyroptosis is a unique proinflammatory programmed cell death process. However, the role of pyroptosis in the development of SC remains unclear, and further study is required. The purpose of this study is to identify pyroptosis-related genes (PRGs) in SC and explore the mechanism of pyroptosis involved in the regulation of SC formation and p… Show more

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