Transcriptomic analysis reveals the effect of the exopolysaccharide of Psychrobacter sp. B-3 on gene expression in RAW264.7 macrophage cells

Zhang, Pingping; Jiang, Li; Yu, Leiye; Wei, Jingfang; Xu, Tong; Sun, Guangling

doi:10.1007/s13131-018-1227-z

Cited by 12 publications

(3 citation statements)

References 31 publications

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“…IITKGP-BTPF3 has demonstrated antioxidant activities via scavenging of superoxide anions and reducing nitric oxide production ( Chatterjee et al, 2018 ). The activity of EPS to activate macrophages ( Zhang et al, 2018 ) and improve cell viabilities ( Yu et al, 2016 ) supports the role EPS’s can play in biomedical fields. Indeed, the role of EPSs from Antarctica isolates on the biogeochemical cycling of calcium and iron in the marine environment, aiding the production and sequestration of dissolved and particulate organic material, aggregation of dust particulates on the surface of the glaciers, and as an essential source of carbon for microorganisms in the food chain have also been recently documented ( Bhaskar and Bhosle, 2005 ; Nagar et al, 2021 ).…”

Section: Biotechnological Advantages Of Extremophilic Eps Over Traditional Biopolymersmentioning

confidence: 84%

Extremophilic Exopolysaccharides: Biotechnologies and Wastewater Remediation

et al. 2021

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Various microorganisms thrive under extreme environments, like hot springs, hydrothermal vents, deep marine ecosystems, hyperacid lakes, acid mine drainage, high UV exposure, and more. To survive against the deleterious effect of these extreme circumstances, they form a network of biofilm where exopolysaccharides (EPSs) comprise a substantial part. The EPSs are often polyanionic due to different functional groups in their structural backbone, including uronic acids, sulfated units, and phosphate groups. Altogether, these chemical groups provide EPSs with a negative charge allowing them to (a) act as ligands toward dissolved cations as well as trace, and toxic metals; (b) be tolerant to the presence of salts, surfactants, and alpha-hydroxyl acids; and (c) interface the solubilization of hydrocarbons. Owing to their unique structural and functional characteristics, EPSs are anticipated to be utilized industrially to remediation of metals, crude oil, and hydrocarbons from contaminated wastewaters, mines, and oil spills. The biotechnological advantages of extremophilic EPSs are more diverse than traditional biopolymers. The present review aims at discussing the mechanisms and strategies for using EPSs from extremophiles in industries and environment bioremediation. Additionally, the potential of EPSs as fascinating biomaterials to mediate biogenic nanoparticles synthesis and treat multicomponent water contaminants is discussed.

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Section: Biotechnological Advantages Of Extremophilic Eps Over Traditional Biopolymersmentioning

confidence: 84%

Extremophilic Exopolysaccharides: Biotechnologies and Wastewater Remediation

et al. 2021

View full text Add to dashboard Cite

show abstract

“…IITKGP-BTPF3 has demonstrated antioxidant activities via scavenging of superoxide anions and reducing nitric oxide production (Chatterjee et al, 2018). The activity of EPS to activate macrophages (Zhang et al, 2018) and improve cell viabilities (Yu et al, 2016) supports the role EPS's can play in biomedical fields. Indeed, the role of EPSs from Antarctica isolates on the biogeochemical cycling of calcium and iron in the marine environment, aiding the production and sequestration of dissolved and particulate organic material, aggregation of dust particulates on the surface of the glaciers, and as an essential source of carbon for microorganisms in the food chain have also been recently documented (Bhaskar and Bhosle, 2005;Nagar et al, 2021).…”

Section: Biotechnological Advantages Of Extremophilic Eps Over Traditional Biopolymersmentioning

confidence: 81%

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“…Agilent 2,100 Bioanalyzer was used to analyze the quality and quantity of cDNA libraries. The Illumina sequencing platform (HiSeqTM 4000) was used to perform the sample library sequencing (23).…”

Section: Illumina Library Construction and Rna Sequencingmentioning

confidence: 99%

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Transcriptomic analysis reveals the effect of the exopolysaccharide of Psychrobacter sp. B-3 on gene expression in RAW264.7 macrophage cells

Cited by 12 publications

References 31 publications

Extremophilic Exopolysaccharides: Biotechnologies and Wastewater Remediation

Extremophilic Exopolysaccharides: Biotechnologies and Wastewater Remediation

Image_1.jpeg

Table_1.xlsx

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