2018
DOI: 10.1142/s0129054118430086
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Transcriptomics: Quantifying Non-Uniform Read Distribution Using MapReduce

Abstract: RNA-seq is a high-throughput Next-sequencing technique for estimating the concentration of all transcripts in a transcriptome. The method involves complex preparatory and post-processing steps which can introduce bias, and the technique produces a large amount of data [7, 19]. Two important challenges in processing RNA-seq data are therefore the ability to process a vast amount of data, and methods to quantify the bias in public RNA-seq datasets. We describe a novel analysis method, based on analysing sequence… Show more

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References 35 publications
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