Transcutaneous Fine Needle Aspiration Biopsy of the Preepiglottic Space

Dedivitis, Rogério Aparecido; Carvalho, Marcos Brasilino de; Rapoport, Abrão

doi:10.1159/000326354

Cited by 10 publications

(4 citation statements)

References 14 publications

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“…Trans-cutaneous fine-needle aspiration cytology (FNAC) and tru-cut biopsy, performed under ultrasound (US) or computed tomography (CT) guidance, have an important role in the diagnostic work-up of the head and neck masses [1][2][3][4]. However, the laryngeal space may not be easily accessible with a transcutaneous approach and biopsies of the masses in this district are usually performed by microlaryngoscopy, in order to obtain material for histological diagnosis and to assess the feasibility of conservative surgery.…”

Section: Introductionmentioning

confidence: 99%

US-guided transcutaneous tru-cut biopsy of laryngo-hypopharyngeal lesions

et al. 2009

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Objective: To evaluate the feasibility and performance of ultrasound-guided transcutaneous tru-cut biopsy (USGTCB) in selected patients (with stenosis of airways or difficult intubation or contraindication to general anaesthesia) with untreated or previously treated suspicious laryngo-hypopharyngeal masses. Methods: Biopsies were performed with a free-hand technique by a single radiologist. Thirty-six USGTCBs were scheduled in 34 patients (24 males, 10 females; age range 47-95 years). Two USGTCBs were not performed, as lesions were not detectable: therefore, 16 USGTCBs were performed for an untreated mass suspicious for malignancy and 18 were performed for a mass suspicious for recurrence after radiotherapy alone, or associated with endoscopic laser surgery or chemotherapy. Results: USGTCB diagnosed 25 squamous cell carcinomas (73.5%) and nine benign lesions (26.5%); no false positives and two false negatives were reported, both in patients previously treated with radiotherapy. The sensitivity, specificity, positive and negative predictive value of the technique was 92.5%, 100%, 100% and 77.7% respectively, with no major complications. Conclusion: Although biopsy under microlaryngoscopy remains the "gold-standard" technique, USGTCB is feasible, carries the advantages of avoiding general anaesthesia, is suitable for outpatients and is cost-effective. If applied to selected patients, it could be considered for the histological diagnosis of both primary and recurrent laryngo-hypopharyngeal masses.

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Section: Introductionmentioning

confidence: 99%

US-guided transcutaneous tru-cut biopsy of laryngo-hypopharyngeal lesions

et al. 2009

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“…If reproducibility is inadequate, there is no practical sense in carrying out studies that include correlation of anatomical and pathological data, as there will be no consensus between professionals on radiological criteria that would suggest preepiglottic invasion. 14 If consensus is lacking, other methods, such as fine needle aspiration, which has been shown to be effective in such cases, 2,15 would be preferable to evaluate tumor invasion of the preepiglottic space.…”

Section: Discussionmentioning

confidence: 99%

Importância da invasão do espaço pré-epiglótico no planejamento terapêutico do câncer da laringe e faringe

Rapoport

Botelho

Souza

et al. 2008

Rev. Bras. Otorrinolaringol.

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The involvement of pre-epiglottis space can change the indication for partial laryngeal resection. Aim: The aim of this study was to evaluate inter-observer and intra-observer agreement by means of computed tomography analysis regarding the involvement of the pre-epiglottis space (PES) from carcinoma of the upper aerodigestive tract and its relation with therapeutic planning. Materials and Methods: Retrospective study of ninety-five computed tomography exams of patients with squamous cell carcinoma, from 1990 to 2004, were selected and evaluated; 87 were males and eight females, with ages ranging from 32 to 73 years. Imaging results were analyzed twice by three radiologists, individually, without any previous knowledge of the clinical stage. No patient had received any previous treatment up to the moment of imaging examination, such as surgery, chemotherapy or radiotherapy. All the cases were confirmed by biopsy. Information was obtained from the medical charts. Results: Kappa Index was calculated by assessing agreement between the three observers. We obtained substantial to almost perfect levels of agreement. Conclusions: After a general Kappa Index of 0.72, the results suggest a substantial agreement in the involvement of the PES by means of computed tomography analysis.

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“…[11][12][13][14] In previous studies involving 10 to 68 patients with new and recurrent laryngeal and hypopharyngeal malignancies, percutaneous US-guided fineneedle aspiration biopsy/core-needle biopsy (US-FNAB/ CNB) yielded a sensitivity of 91.9% to 92.5% and specificity of 100%. [11][12][13] Although these studies showed excellent results in terms of diagnostic accuracy, no study has evaluated the time-and cost-effectiveness of US-FNAB/CNB for LHSCC diagnosis. Therefore, we aimed to evaluate the benefits in terms of time and cost of US-FNAB/CNB for LHSCC diagnosis by comparing them with those of conventional DLB under general anesthesia.…”

mentioning

confidence: 99%

“…Although ultrasound (US) examination has been conventionally considered to have limited capacity for evaluation of the larynx and pharynx, several studies have shown the diagnostic utility of US examination and US-guided diagnostic procedures in LHSCC. [11][12][13][14] In previous studies involving 10 to 68 patients with new and recurrent laryngeal and hypopharyngeal malignancies, percutaneous US-guided fineneedle aspiration biopsy/core-needle biopsy (US-FNAB/ CNB) yielded a sensitivity of 91.9% to 92.5% and specificity of 100%. [11][12][13] Although these studies showed excellent results in terms of diagnostic accuracy, no study has evaluated the time-and cost-effectiveness of US-FNAB/CNB for LHSCC diagnosis.…”

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confidence: 99%

Time and Cost of Ultrasound‐Guided Fine‐Needle Aspiration Biopsy/Core‐Needle Biopsy for Primary Laryngohypopharyngeal Squamous Cell Carcinoma

Ahn

Lee

Sohn

2020

Otolaryngol.--head neck surg.

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Objectives This study aimed to evaluate benefits in terms of time and cost of percutaneous ultrasound-guided fine-needle aspiration biopsy/core-needle biopsy (US-FNAB/CNB) for the diagnosis of primary laryngeal and hypopharyngeal squamous cell carcinoma (LHSCC) in comparison with direct laryngoscopic biopsy (DLB) under general anesthesia. Study Design Retrospective case-control study. Setting Single operator of a single center. Subjects and Methods From 2018 to 2019, 28 patients who underwent percutaneous US-FNAB/CNB for the diagnosis of untreated LHSCC were enrolled. All US-FNAB/CNBs were performed in the outpatient department by a single head and neck surgeon. Their results were compared with those of 27 patients who underwent DLB under general anesthesia. Results No major complications occurred in the US-FNAB/CNB and DLB groups. Time to biopsy, time to pathologic diagnosis, and time to treatment initiation in the US-FNAB/CNB and DLB groups were 0 and 14 days ( P < .001), 7 and 20 days ( P < .001), and 24 and 35 days ( P = .001), respectively. Procedure-related costs were $368.5 and $981.0 in the US-FNAB/CNB and DLB groups ( P < .001). Conclusions US-FNAB/CNB offers true benefits in terms of time and cost over those given by conventional DLB for diagnosis of LHSCC in indicated patients.

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Transcutaneous Fine Needle Aspiration Biopsy of the Preepiglottic Space

Cited by 10 publications

References 14 publications

US-guided transcutaneous tru-cut biopsy of laryngo-hypopharyngeal lesions

US-guided transcutaneous tru-cut biopsy of laryngo-hypopharyngeal lesions

Importância da invasão do espaço pré-epiglótico no planejamento terapêutico do câncer da laringe e faringe

Time and Cost of Ultrasound‐Guided Fine‐Needle Aspiration Biopsy/Core‐Needle Biopsy for Primary Laryngohypopharyngeal Squamous Cell Carcinoma

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