Transcutaneous measurement of arterial oxygen partial pressure during anaesthesia with prolonged artificial ventilation

Stosseck, Klaus; Hugh, R.; Huch, A.; Lübbers, D. W.; Frey, Richard

doi:10.1016/0300-9572(74)90032-x

Cited by 6 publications

(1 citation statement)

References 2 publications

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“…However, we did not find any study reporting TcpO 2 values in patients with central circulatory failure. It is of note that Stosseck et al, reported that large changes of blood pressure did not influence the TcpO 2 until the systolic pressure fell <90 mmHg, and that a further 10-mmHg decrease of systolic pressure caused an additional 10% underestimation of TcpO 2 [28]. As blood pressure and SpO 2 may be easily measured during TcpO 2 recording to eliminate respiratory insufficiency or central circulatory failure, this suggests that RPI is not of particular importance.…”

Section: Discussionmentioning

confidence: 97%

Reference Probe for TcpO2 at Rest: A Systematic Review

2022

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(1) Background: Transcutaneous oxygen pressure (TcpO2) is used to determine the severity of lower extremity arterial disease (LEAD). Many authors used a ratio of limb to chest TcpO2, also called the regional perfusion index (RPI), which should be independent of variations in oxygen delivery and reflective of local limb oxygen supply. The relevance of a reference probe-positioned TcpO2 electrode is debated. We aimed to review the relevance of the reference probe in previous studies using rest TcpO2. (2) Methods: We searched Medline and the Cochrane Central Register of Controlled Trials on 22 September 2022 using keywords related to TcpO2, reference probe and LEAD. (3) Results/Discussion: Fifteen studies were included in the review. Nine studies investigated LEAD severity (n = 9), amputation healing predication (n = 4), surgical outcome prediction (n = 2), therapeutic effect (n = 3) and difference according to diabetic status (n = 1). Four studies investigated more than 1 indication. Among 12 (16.7%) studies using RPI, only two authors found a benefit of using RPI instead of absolute TcpO2. Using only univariate analysis, one author reported that RPI was significantly related to viability at 1 year, while distal TcpO2 was not, on 13 limbs. The following year, the same author published a new study including 118 limbs that reported that RPI and absolute TcPO2 were both prognostic factors for limb viability at 1 year using a multivariate model. (4) Conclusions: Only one study firmly supporting the use of RPI, calculated using a reference probe on the arm, to predict BKA healing. Prospective studies are needed to validate this result; for other indications there is insufficient data supporting the use of a TcpO2 reference probe at rest.

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Section: Discussionmentioning

confidence: 97%