Transcutaneous Oxygen and Carbon Dioxide during the First Half Year of Life in Premature and Normal Term Infants

Hoppenbrouwers, Toke; Hodgman, Joan E.; Arakawa, Kazuko; Durand, Manuel; Cabal, Luis A

doi:10.1203/00006450-199201000-00014

Cited by 18 publications

(3 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Usually, a combined oxygen ( P O 2 )/carbon dioxide ( P CO 2 ) tension skin probe equipped with Clark and Stow–Severinghaus electrodes is used to measure P tc,O 2 and P tc,CO 2 after “arteriolization” of the skin by warming to a temperature between 41°C and 45°C. In the newborn, because of skin thinness, transcutaneous values of oxygen and carbon dioxide approach the pressures in arterial blood [1]. The main advantage is the real‐time estimation over prolonged periods of time without necessity of blood sampling.…”

mentioning

confidence: 99%

Validity of transcutaneous oxygen/carbon dioxide pressure measurement in the monitoring of mechanical ventilation in stable chronic respiratory failure

Rosner¹,

Hannhart²,

Chabot³

et al. 1999

Eur Respir J

View full text Add to dashboard Cite

The accuracy and precision of transcutaneous pressure measurements of oxygen (Ptc,O2) and carbon dioxide (Ptc,CO2) in the monitoring of nocturnal assisted ventilation in adult patients were evaluated. Transcutaneous measurements obtained with two analysers, Radiometer TINA‐TCM3 (R) and Kontron MicroGas‐7650 (K), were compared with arterial blood gases analysed in blood samples withdrawn simultaneously in 10 patients. Sensors were heated to 43°C. Measurements of trascutaneous blood gases and arterial blood gases were collected six times at 1‐h intervals. The data obtained with both instruments were similar and did not significantly change over the 5 h test period. Measurement of Ptc,O2 underestimated arterial oxygen tension (Pa,O2) and this underestimation increased with the level of Pa,O2 (p<0.01). Measurements of Ptc,CO2 overestimated arterial carbon dioxide tension (Pa,CO2) and this overestimation increased with the level of Pa,CO2 (p<0.05). These errors suggested an instrumental bias. Mathematical correction of this bias neutralized the error in accuracy and improved the precision ( sd of the differences transcutaneous blood gases ‐ arterial blood gases). An additional correction, suppressing the between‐subject scattering, improved the actual precision: precision was reduced from 1.9 to 0.8 kPa (14.4 to 5.7 mmHg) (R) and from 1.7 to 0.5 kPa (13.1 to 3.7 mmHg) (K) for oxygen, and from 1.0 kPa (7.8 mmHg) (R) and 0.7 kPa (5.6 mmHg) (K) to 0.4 kPa (3.2 mmHg) for carbon dioxide (R and K). In conclusion, with these two successive corrections, transcutaneous oxygen and carbon dioxide provide a reliable estimation of blood gases to monitor nocturnal ventilation in adults with chronic respiratory failure.

show abstract

mentioning

confidence: 99%

Validity of transcutaneous oxygen/carbon dioxide pressure measurement in the monitoring of mechanical ventilation in stable chronic respiratory failure

Rosner¹,

Hannhart²,

Chabot³

et al. 1999

Eur Respir J

View full text Add to dashboard Cite

show abstract

“…From the box plot for the mean in Figure 1, the median of the means of the 31 babies at 36 weeks PMA is 97.2%. Other studies had included preterm babies with respiratory disorders [2–12], babies monitored within a laboratory setting [16], babies studied at 37 and 43 weeks PMA [17], and babies followed up at three-month intervals over the first 12-month postdelivery period [18]. Median or median baseline oxygen saturation levels ranging from 96.25% to 100% were obtained in these studies.…”

Section: Discussionmentioning

confidence: 99%

An Exploratory Investigation of Some Statistical Summaries of Oximeter Oxygen Saturation Data from Preterm Babies

et al. 2011

View full text Add to dashboard Cite

Aim. To explore the potential usefulness of the mean, standard deviation (SD), and coefficient of variation (CV = SD/mean) of oximeter oxygen saturations in the clinical care of preterm babies. Methods. This was an exploratory investigation involving 31 preterm babies at 36 weeks postmenstrual age. All babies were healthy, but two were considered to be clinically unstable and required greater attention. Each baby's oxygen saturations were recorded using an oximeter and summarized by the mean, SD, and CV. The potential usefulness of each measure was assessed by its ability to distinguish the two unstable babies from the others. This was achieved using box plots and hierarchical clustering together with the Calinski-Harabasz (CH) index to quantify clustering performance (higher CH index indicates stronger clustering outcome). Results. The box plots flagged both unstable babies as outliers and none of the other babies. Successful clustering of the stable and unstable babies was achieved using the CV (CH = 72.8) and SD (CH = 63.3) but not with the mean. Conclusion. Taking the box plots and clustering results together, it seems plausible that variability might be more effective than mean level for detecting instability in oxygen saturation in preterm babies and that the combination of variability and level through the CV might be even better.

show abstract

“…This is reflected in changes in blood gas measurements. When measured continuously overnight, PaCO 2 decreases in the first 3 months of life (16,17) and baseline PaO 2 increases over the first 4 weeks of life (18,19). Episodes of oxygen desaturation greater than 4% are relatively infrequent in the first week of life and then become more frequent during the second to fourth weeks of life (19).…”

Section: Apnea In Term Infantsmentioning

confidence: 99%

Methylxanthines for the treatment of apnea associated with bronchiolitis and anesthesia

McNamara

Nixon

Anderson

2004

Pediatric Anesthesia

View full text Add to dashboard Cite

Transcutaneous Oxygen and Carbon Dioxide during the First Half Year of Life in Premature and Normal Term Infants

Cited by 18 publications

References 25 publications

Validity of transcutaneous oxygen/carbon dioxide pressure measurement in the monitoring of mechanical ventilation in stable chronic respiratory failure

Validity of transcutaneous oxygen/carbon dioxide pressure measurement in the monitoring of mechanical ventilation in stable chronic respiratory failure

An Exploratory Investigation of Some Statistical Summaries of Oximeter Oxygen Saturation Data from Preterm Babies

Methylxanthines for the treatment of apnea associated with bronchiolitis and anesthesia

Contact Info

Product

Resources

About