Transdiagnostic group cognitive behaviour therapy for anxiety in bipolar disorder—a pilot feasibility and acceptability study

Perich, Tania; Mitchell, Philip B.; Meade, Tanya

doi:10.1186/s40814-020-00719-6

Cited by 5 publications

(1 citation statement)

References 25 publications

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“…Other than pharmacological treatment or disorder specific psychological therapy, another approach to combating the high rates of comorbidity present in BD, and potentially helping to reduce relapse rates, is to adopt transdiagnostic treatment protocols for BD patients. Early feasibility trials assessing transdiagnostic approaches show promising results (Perich et al 2020 ), however, further research, such as RCTs, are needed to better determine their effectiveness. Network analyses, which provides centrality statistics that indicate how variables are related to others in the network, may also be useful for BD given that symptoms overlap with various other psychiatric disorders (Scott et al 2021 ).…”

Section: Discussionmentioning

confidence: 99%

Rates and associations of relapse over 5 years of 2649 people with bipolar disorder: a retrospective UK cohort study

Hett,

Morales-Muñoz,

Durdurak

et al. 2023

Int J Bipolar Disord

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Background Evidence regarding the rate of relapse in people with bipolar disorder (BD), particularly from the UK, is lacking. This study aimed to evaluate the rate and associations of clinician-defined relapse over 5 years in a large sample of BD patients receiving routine care from a UK mental health service. Method We utilised de-identified electronic health records to sample people with BD at baseline. Relapse was defined as either hospitalisation, or a referral to acute mental health crisis services, between June 2014 and June 2019. We calculated the 5-year rate of relapse and examined the sociodemographic and clinical factors that were independently associated with relapse status and the number of relapses, over the 5-year period. Results Of 2649 patients diagnosed with BD and receiving care from secondary mental health services, 25.5% (n = 676) experienced at least one relapse over 5 years. Of the 676 people who relapsed, 60.9% experienced one relapse, with the remainder experiencing multiple relapses. 7.2% of the baseline sample had died during the 5-year follow-up. Significant factors associated with experiencing any relapse, after adjustment for relevant covariates, were history of self-harm/suicidality (OR 2.17, CI 1.15–4.10, p = 0.02), comorbidity (OR 2.59, CI 1.35–4.97, p = 0.004) and psychotic symptoms (OR 3.66, CI 1.89–7.08, p < 0.001). Factors associated with the number of relapses over 5 years, after adjustment for covariates, were self-harm/suicidality (β = 0.69, CI 0.21–1.17, p = 0.005), history of trauma (β = 0.51, CI = 0.07–0.95, p = 0.03), psychotic symptoms (β = 1.05, CI 0.55–1.56, p < 0.001), comorbidity (β = 0.52, CI 0.07–1.03, p = 0.047) and ethnicity (β = − 0.44, CI − 0.87 to − 0.003, p = 0.048). Conclusions Around 1 in 4 people with BD in a large sample of people with BD receiving secondary mental health services in the UK relapsed over a 5-year period. Interventions targeting the impacts of trauma, suicidality, presence of psychotic symptoms and comorbidity could help to prevent relapse in people with BD and should be considered in relapse prevention plans.

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Section: Discussionmentioning

confidence: 99%

Rates and associations of relapse over 5 years of 2649 people with bipolar disorder: a retrospective UK cohort study

Hett,

Morales-Muñoz,

Durdurak

et al. 2023

Int J Bipolar Disord

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Factors Associated with Prospective Acceptability and Preferences for Unified Transdiagnostic Cognitive-Behavioral Treatments and Group Therapy in the Portuguese General Population

Pedro,

de Oliveira,

Pereira

et al. 2024

Adm Policy Ment Health

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Group transdiagnostic cognitive-behavioral therapy (CBT) offers a promising solution for limited mental health access in Portugal. Understanding barriers to patient adherence is crucial for successful implementation. This study aimed to characterize the prospective acceptability and preferences for unified transdiagnostic CBT and group therapy in the Portuguese general population and explore their correlates. A sample of 243 participants (18–88 years old), recruited online, completed an online survey collecting information on sociodemographic and clinical characteristics, acceptability of transdiagnostic CBT treatments, specifically of Unified Protocol (UP), acceptability of group therapy, therapeutic format preferences, beliefs about group therapy and help-seeking attitudes. Most participants were receptive to and perceived as useful both unified transdiagnostic CBT and group therapy. Overall, participants presented significantly more favorable attitudes than unfavorable attitudes toward unified transdiagnostic CBT and group therapy (p < .001). Multivariate analyses revealed that (1) favorable attitudes toward transdiagnostic treatments were negatively associated with being employed and positively associated with living in an urban area, and higher efficacy scores; (2) unfavorable attitudes toward transdiagnostic treatments were positively associated with being married/cohabitating and negatively associated with vulnerability scores; (3) being female, living in an urban area, and higher efficacy and myth scores emerged as positive predictors of favorable attitudes toward group therapy; and (4) efficacy and vulnerability scores and help-seeking propensity emerged as negative predictors of unfavorable attitudes toward group therapy. These findings highlight the importance of delineating strategies to increase knowledge and acceptance of unified transdiagnostic CBT and group therapy in the Portuguese population, addressing specific individual characteristics.

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Anxiety in bipolar disorder: A review of publication trends

Larocque

Fortin-Vidah

Angers

et al. 2023

Journal of Affective Disorders

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Transdiagnostic group cognitive behaviour therapy for anxiety in bipolar disorder—a pilot feasibility and acceptability study

Cited by 5 publications

References 25 publications

Rates and associations of relapse over 5 years of 2649 people with bipolar disorder: a retrospective UK cohort study

Rates and associations of relapse over 5 years of 2649 people with bipolar disorder: a retrospective UK cohort study

Factors Associated with Prospective Acceptability and Preferences for Unified Transdiagnostic Cognitive-Behavioral Treatments and Group Therapy in the Portuguese General Population

Anxiety in bipolar disorder: A review of publication trends

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