Transducer for harmonic intravascular ultrasound imaging

Vos, Hendrik J.; Frijlink, M.A.; Droog, E.; Goertz, David E.; Blacquière, Gerrit; Gisolf, A.; Jong, Nico de; Steern, A.F.W. van der

doi:10.1109/tuffc.2005.1563286

Cited by 42 publications

(19 citation statements)

References 15 publications

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“…Conventional IVUS elements have a bandwidth that is too limited for optimal harmonic imaging though. A new generation single crystal technology or composite transducers based on dual resonance layers (capacitive micromachined ultrasound transducers or CMUTs) are under development [72][73][74]. The harmonic IVUS system that approaches current IVUS practice employs filtered transmission and reception of signals.…”

Section: Intravascular Ultrasound Vasa Vasorum Imagingmentioning

confidence: 99%

Vascular ultrasound for atherosclerosis imaging

2011

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Cardiovascular disease is a leading cause of death in the Western world. Therefore, detection and quantification of atherosclerotic disease is of paramount importance to monitor treatment and possible prevention of acute events. Vascular ultrasound is an excellent technique to assess the geometry of vessel walls and plaques. The high temporal as well as spatial resolution allows quantification of luminal area and plaque size and volume. While carotid arteries can be imaged non-invasively, scanning of coronary arteries requires invasive intravascular catheters. Both techniques have already demonstrated their clinical applicability. Using linear array technology , detection of disease as well as monitoring of pharmaceutical treatment in carotid arteries are feasible. Data acquired with intravascular ultrasound catheters have proved to be especially beneficial in understanding the development of atherosclerotic disease in coronary arteries. With the introduction of vascular elastography not only the geometry of plaques but also the risk for rupture of plaques might be identified. These so-called vulnerable plaques are frequently not flow-limiting and rupture of these plaques is responsible for the majority of cerebral and cardiac ischaemic events. Intravascular ultrasound elastography studies have demonstrated a high correlation between high strain and vulnerable plaque features, both ex vivo and in vivo. Additionally, pharmaceutical intervention could be monitored using this technique. Non-invasive vascular elastography has recently been developed for carotid applications by using compound scanning. Validation and initial clinical evaluation is currently being performed. Since abundance of vasa vasorum (VV) is correlated with vulnerable plaque development, quantification of VV might be a unique tool to even prevent this from happening. Using ultrasound contrast agents, it has been demonstrated that VV can be identified and quantified. Although far from routine clinical application, non-invasive and intravascular ultrasound VV imaging might pave the road to prevent atherosclerotic disease in an early phase. This paper reviews the conventional vascular ultrasound techniques as well as vascular ultrasound strain and vascular ultrasound VV imaging.

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Section: Intravascular Ultrasound Vasa Vasorum Imagingmentioning

confidence: 99%

Vascular ultrasound for atherosclerosis imaging

2011

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“…The frequency of the second harmonic signal lies in the diminished frequency range of the transducer's bandwidth. a transducer for intravascular second-harmonic imaging, showing a frequency response with two peaks around 20 and 40 MHz, has been designed, fabricated, and characterized [16]. The design of dual-frequency transducer element was improved and mounted onto an IVUs catheter [17].…”

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confidence: 99%

Demonstration of second-harmonic IVUS feasibility with focused broadband miniature transducers

Chandrana

Kharin

Vince

et al. 2010

IEEE Trans. Ultrason., Ferroelect., Freq. Contr.

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Focused broadband miniature polyvinylidene fluoride-trifluoroethylene (PVDF TrFE) ultrasonic transducers were investigated for intravascular (IVUS) second-harmonic imaging. Modeling and experimental studies demonstrated that focused transducers, unlike conventional flat transducers, build up second harmonic peak pressures faster and stronger, leading to an increased SNR of second harmonic content within the coronary geometry. Experimental results demonstrated that focused second harmonic pressures could be controlled to occur at specific depths by controlling the f-number of the transducer. The experimental results were in good agreement with the modeled results. Experiments were conducted using three imaging modalities: fundamental 20 MHz (F20), second harmonic 40 MHz (H40), and fundamental 40 MHz (F40). The lateral resolutions for a 1-mm transducer (f-number 3.2) at F20, F40, and H40 were experimentally measured to be 162, 123, and 124 microm, respectively, which agreed well with the theoretical calculations with <<8% error. Lateral resolution was further characterized in the three modes, using a micromachined phantom consisting of fixed bars and spaces with widths ranging from 20 to 160 microm. H40 exhibited better lateral resolution, clearly displaying 40- and 60-microm bars with about 4 dB and 7 dB greater signal strength compared with F20. Ex vivo human aorta images were obtained in the second-harmonic imaging mode to show the feasibility of high resolution second-harmonic IVUS using focused transducers.

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“…88 The concept of dual frequency transducers have been demonstrated by several researchers. [92][93][94][95] In regular transducers there is always a trade-off between the ultrasound beam penetration depth and image resolution. On the other hand, in dual frequency transducers, the low frequency transmit element provides a deep penetration while the high frequency receive element creates an image with enhanced resolution.…”

Section: Linbo 3 -Based Transducersmentioning

confidence: 99%

Lead-free piezoelectric materials and ultrasonic transducers for medical imaging

2015

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Piezoelectric materials have been vastly used in ultrasonic transducers for medical imaging. In this paper, firstly, the most promising lead-free compositions with perovskite structure for medical imaging applications have been reviewed. The electromechanical properties of various lead-free ceramics, composites, and single crystals based on barium titanate, bismuth sodium titanate, potassium sodium niobate, and lithium niobate are presented. Then, fundamental principles and design considerations of ultrasonic transducers are briefly described. Finally, recent developments in lead-free ultrasonic probes are discussed and their acoustic performance is compared to lead-based transducers. Focused transducers with different beam focusing methods such as lens focusing and mechanical shaping are explained. Additionally, acoustic characteristics of lead-free probes including the pulse-echo results as well as their imaging capabilities for various applications such as phantom imaging, in vitro intravascular ultrasound imaging of swine aorta, and in vivo or ex vivo imaging of human eyes and skin are reviewed.

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Transducer for harmonic intravascular ultrasound imaging

Cited by 42 publications

References 15 publications

Vascular ultrasound for atherosclerosis imaging

Vascular ultrasound for atherosclerosis imaging

Demonstration of second-harmonic IVUS feasibility with focused broadband miniature transducers

Lead-free piezoelectric materials and ultrasonic transducers for medical imaging

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