2005
DOI: 10.1007/s00403-005-0541-4
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Transepidermal water loss and skin capacitance alterations among workers in an ultra-low humidity environment

Abstract: No studies have been performed evaluating skin barrier alterations in humans exposed to ultra-low humidity (ULH) in spite of several lines of evidence from animal experiments suggesting that the skin barrier is altered on exposure to ULH. The objectives of this study were to assess barrier function changes in workers occupationally exposed to ULH (relative humidity 1.5%), and to evaluate whether the exposure duration shows a dose-response relationship with transepidermal water loss (TEWL) and skin capacitance.… Show more

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Cited by 35 publications
(38 citation statements)
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“…Studies on health effects of ultra-low environmental humidity (<5%) are limited but have generally observed adverse effects on the skin [6][7][8][9] . There are relatively more studies on the effects of RH in the 5% to 30% range, and they have generally found skin effects as well, especially in people with pre-existing atopic eczema [12][13][14][15][16][17][18] .…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Studies on health effects of ultra-low environmental humidity (<5%) are limited but have generally observed adverse effects on the skin [6][7][8][9] . There are relatively more studies on the effects of RH in the 5% to 30% range, and they have generally found skin effects as well, especially in people with pre-existing atopic eczema [12][13][14][15][16][17][18] .…”
Section: Discussionmentioning
confidence: 99%
“…Many clean room workers even reduce their water intake in order to minimize the need to go the bathroom at work [1][2][3] . Previous studies found working in environments with ultra-low humidity (relative humidity [RH]=1.5%) may cause skin symptoms, changes in skin functions, and even disorders such as xerotic eczema [4][5][6][7][8] . A study in Japan on workers working in environments with very low humidity also observed high prevalence of atopic dermatitis and skin dryness 9) .…”
mentioning
confidence: 99%
“…A majority of studies investigated skin dryness in offices and workplaces (Reinikainen et al, 1991;Nordström et al, 1994;Reinikainen and Jaakkola, 2003;Chou et al, 2005;Chou et al, 2007), with a few laboratory studies conducted in environmental chambers (Sunwoo et al, 2006a;Wyon et al, 2006). This literature review focused on healthy subjects without underlying conditions such as eczema (Eberlein-König et al, 1996).…”
Section: Skin Drynessmentioning
confidence: 99%
“…The most commonly studied aspect of extrinsic aging is the exposure of skin to ultraviolet radiation which causes skin damage and erythema by creating reactive oxygen species and DNA damage [1]. However, various other extrinsic factors exist including smoking, alcohol consumption, ozone, climate, and geography; for example, changes in skin have been noted at extremely low humidity (relatively humidity [RH] <1.5%) [2] and high altitude (>2900 m) [3].…”
Section: Introductionmentioning
confidence: 99%