Transformation of the acute myeloid leukemia to acute B cell lymphoblastic leukemia with CAR-T cell therapy: a case report and review of the literature

Abstract

Lineage conversion is used to describe acute myeloid or lymphoid leukemia becomes the opposite at relapse.We report a 4-year-old child with acute myeloid leukemia who was converted to acute lymphoblastic leukemia at relapse and received chimeric antigen receptor T (cell) therapy for reference.