“…Postoperative pain can lead to anxiety, unease, alterations of the endocrine system, and delayed postsurgical recovery of internal organs. In severe cases, these can increase the risk of serious complications, including myocardial ischemia, accelerated heart rate, pulmonary dysfunction, deep vein thrombosis, and decreased immune function, all of which negatively impact patient prognosis (4,5). In addition, postoperative pain, if not fully controlled upon onset, may develop into chronic pain and affect the function of multiple organ systems (6).…”