The healthcare sector has undergone a significant transformation with the emergence of telemedicine and remote monitoring technologies. Telemedicine uses technology to provide healthcare services from a distance, breaking down geographical barriers and making medical care more accessible. In this chapter, the author provides a foundational understanding of these innovations, starting with an overview of telemedicine and remote patient monitoring. Then the author explores their applications in healthcare, encompassing virtual consultations, real-time patient data monitoring, diagnostics, treatment adherence, and chronic disease management. The exploration spans various applications of telemedicine, from real-time video consultations to AI-driven diagnostic support. Furthermore, its benefits, addressing challenges, including privacy considerations and regulatory frameworks, underscoring the need for a balanced approach to ensure equitable, secure, and patient-centric solutions, technological limitations, future trends, and some case studies are discussed in this chapter.