Transfusion-Associated Graft versus Host Disease in A Previously Healthy Individual Who Received Transfusion from A First Degree Relative

Abstract

ÖzetDaha önce sağlıklı olan, mide kanaması sonrası birinci derece akrabasından bir ünite kan transfüzyonu yapılan 56 yaşında-ki erkek hasta, transfüzyondan iki hafta sonra deri döküntüsü, yüksek ateş, sarılık, halsizlik şikayeti ile kliniğimize başvurdu. Takiplerinde hastaya transfüzyona bağlı graft versus host hastalığı tanısı konularak, metilprednizolon ve siklosporin tedavisi başlandı. Tedaviye yanıt alınamayan hasta kaybedildi. AbstractA previously healthy 56-year-old man who had received a unit of blood transfusion from his fi rst degree relative after gastrointestinal system bleeding, was admitted to our clinic with complaints of rash, fever, jaundice and nausea two weeks after transfusion. The patient was diagnosed as having transfusion-associated graft versus host disease and methylprednisolone and cyclosporin therapy was given. The patient failed to respond to therapy and died.