Transfusion Related Hepatitis C Virus Antibodies and Possible Risk Factors in Healthy Blood Donors.

Abdaltif, Abdoalrhman; Abdallah, Mohammed Degail; Yagowb, Marwa Yousif; Mustafa, Mustafa Gamal; Alameen, Taha Algilani; Attar, Ahmed Osman Gasim; Abdelgani, Sara; Eltayeb, Lienda Bashier

doi:10.51847/ce9m7yp4rc

Cited by 5 publications

(6 citation statements)

References 24 publications

(25 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, when expressed per the population reported in this category (blood donors), only 0.93% of the HCVAb positive cases were found in blood donors, which is much lower than previously reported (4.3%) from the same department in this hospital [16]. Even though, this prevalence of HCVAb is still higher than that reported in the capital Riyadh (0.4%) and the Eastern province of Saudi Arabia (0.59%) and in niehbouring countries (0.16%) [23][24][25].…”

Section: Resultsmentioning

confidence: 53%

Frequency of Hepatitis C Infection in Hospital Patients in Ha'il, KSA: A Retrospective Analysis

Zrieq¹,

Algahtani²,

Ali³

et al. 2022

Int J Pharm Res Allied Sci

View full text Add to dashboard Cite

Few studies have assessed the prevalence of hepatitis C infection in the general population of Ha'il in KSA or among hospital patients. This study aimed to evaluate the prevalence, correlates, and patterns of HCV antibodies among individuals attending King Khalid general hospital. A retrospective analysis was applied to evaluate HCV seropositivity among individuals who attended a tertiary care system from June 2020 to June 2021 in the Ha'il region, KSA. Clinical and demographic data of 3861 patients for HCV seropositivity tests were collected and analyzed using Excel and the statistical package for social sciences (SPSS) programs. The association in categorical variables was tested using the chi-squared (χ2) test. The level of statistical significance for the study was set at p < 0.05. The rate of HCVAb among hospital patients was 1.4%, with the majority 65% being females. A statistically significant association was; however, observed between HCV seropositivity and age, medical department as well as the epidemiological month. The rate of HCV seropositive was found significantly increased in the age group 31-40 (0.44%), dialysis patients (0.6%), and during March 2021(0.35%). The rate of hepatitis C infection is still worrying among hospital patients in Ha'il. Strict universal precautions should be employed in hospitals and dialysis units to prevent HCV transmission.

show abstract

Section: Resultsmentioning

confidence: 53%

Frequency of Hepatitis C Infection in Hospital Patients in Ha'il, KSA: A Retrospective Analysis

Zrieq¹,

Algahtani²,

Ali³

et al. 2022

Int J Pharm Res Allied Sci

View full text Add to dashboard Cite

show abstract

“…In rats of the older group, there was a significant decrease in the amount of disk-shaped erythrocytes in the blood (Abdaltif et al, 2021;Ahmed, 2021). At the same time, in the blood of these rats, there was an excess of erythrocytes having a changed shape.…”

Section: Resultsmentioning

confidence: 87%

“…The level of plasma lipid peroxidation was assessed in the course of determining the active substances contained in plasma using a kit manufactured by Agat-Med (Russia) and by the content of acyl hydroperoxides in plasma (Ashtiani et al, 2021;Ong et al, 2021). In all cases, the level of plasma antioxidant activity was determined (Abdaltif et al, 2021). The level of lipid peroxidation processes in erythrocyte structures was recorded by the content of malondialdehyde and acyl hydroperoxides in them.…”

Section: Methodsmentioning

confidence: 99%

Physiological Features of Erythrocytes in the Aging Organism

Tkacheva¹,

Медведев²,

Vorobyeva³

et al. 2023

J Biochem Technol

View full text Add to dashboard Cite

The progression of aging affects various blood parameters, which can weaken the viability of the body. Clarification of various aspects of this process requires additional observations, especially with the use of animals. The study was conducted on 43 healthy outbred male rats aged 24 months. Also, 32 healthy outbred male rats 3 months old, which formed the control group, were taken under observation. The examined 24-month-old rats showed standard aging phenomena. In their erythrocytes, there was an increase in lipid peroxidation caused by a weakening of the activity of their antioxidant defense. In the blood of two-year-old rats, there was a decrease in the level of erythrocyte-discocytes. This was accompanied in them by an excess content of erythrocytes in the blood, which had a changed shape to varying degrees. In rats of the older group, erythrocyte aggregation was increased, as indicated by an increase in the numberof erythrocytes that entered the aggregates in the blood and an increase in the number of most erythrocyte aggregates with a decrease in the level of free erythrocytes. For two-year-old rats, low content of erythrocytesdisconcytes in the blood and an excess number of erythrocytes with a modified shape, as well as an increase in their aggregation, are characteristics. An important reason for these changes is the weakening of the antioxidant protection of erythrocytes, leading to a pronounced activation of lipid peroxidation in them.

show abstract

“…The Hepatitis C virus (HCV) is a significant issue of public health that impacts 170 million people globally. It represents the most prevalent cause of chronic hepatitis, cirrhosis, and liver cancer worldwide, as well as the principal reason for liver transplants [1,2], and some research revealed that HCV-related mortality (death from liver failure or hepatocellular carcinoma) will keep going up throughout the next couple of decades [3]. Hepatitis C virus (HCV) infection is getting more widespread all over the world.…”

Section: Introductionmentioning

confidence: 99%

Genomic divergence of Hepatitis C virus towards common prescribed interferon regimens on sustained virologic response (SVR) ‎

Eltayeb¹,

Fallatah²,

Mangi³

2022

J Adv Pharm Educ Res

Self Cite

View full text Add to dashboard Cite

show abstract

Transfusion Related Hepatitis C Virus Antibodies and Possible Risk Factors in Healthy Blood Donors.

Cited by 5 publications

References 24 publications

Frequency of Hepatitis C Infection in Hospital Patients in Ha'il, KSA: A Retrospective Analysis

Frequency of Hepatitis C Infection in Hospital Patients in Ha'il, KSA: A Retrospective Analysis

Physiological Features of Erythrocytes in the Aging Organism

Genomic divergence of Hepatitis C virus towards common prescribed interferon regimens on sustained virologic response (SVR) ‎

Contact Info

Product

Resources

About