Transfusion‐related sepsis due to <i>Serratia liquefaciens</i> in the United States

These guidelines have been developed for practitioners who insert catheters and for persons responsible for surveillance and control of infections in hospital, outpatient, and home health-care settings. This report was prepared by a working group comprising members from professional organizations representing the disciplines of critical care medicine, infectious diseases, health-care infection control, surgery, anesthesiology, interventional radiology, pulmonary medicine, pediatric medicine, and nursing. The These guidelines are intended to provide evidencebased recommendations for preventing catheter-related infections. Major areas of emphasis include 1) educating and training health-care providers who insert and maintain catheters; 2) using maximal sterile barrier precautions during central venous catheter insertion; 3) using a 2% chlorhexidine preparation for skin antisepsis; 4) avoiding routine replacement of central venous catheters as a strategy to prevent infection; and 5) using antiseptic/antibiotic impregnated short-term central venous catheters if the rate of infection is high despite adherence to other strategies (i.e., education and training, maximal sterile barrier precautions, and 2% chlorhexidine for skin antisepsis). These guidelines also identify performance indicators that can be used locally by health-care institutions or organizations to monitor their success in implementing these evidence-based recommendations.

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“…Category IB 3. Complete infusions of blood or other blood products within 4 hours of hanging the blood [231][232][233][234]. Category II 4.…”

Section: Category Ib II Surveillancementioning

confidence: 99%

Guidelines for the prevention of intravascular catheter-related infections

O’Grady¹,

Alexander²,

Dellinger³

et al. 2002

American Journal of Infection Control

636

843

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“…Serratia is also a Gram-negative bacterium, which proliferates easily in poor environment at +4 -+22 o C. The bacteria were isolated from both red blood cell concentrates and platelets concentrates. Transmitting Serratia, especially Serratia liquefaciens, causes transfusionassociate sepsis, most often fatal (1,20). A prospective analysis of bacterial cultures from whole blood and red blood cell concentrates has shown that bacterial contamination is much more common in blood components, i.e.…”

Section: Bacterial Infections Transmitted With Red Blood Cell Concentmentioning

confidence: 99%

Transfusion-Associated Bacterial Sepsis

Korsak¹

2012

Severe Sepsis and Septic Shock - Understanding a Serious Killer

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“…Although rare, bacterial contamination of stored autologous units can rarely cause sepsis and death (Dodd 1992;Roth 2000) and is also subject to all the potential clerical/procedural errors as allogeneic blood albeit avoiding the hazards of TTIs and immunological hazards associated with allogeneic transfusion. It also requires a weekly commitment from the patient and involves a weekly appointment at the donation site, in addition to staffing, other practical issues and related costs of the PABD programme.…”

Section: Preoperative Autologous Blood Donation (Pabd)mentioning

confidence: 99%