Transgenerational trauma, the transmission of psychological and emotional wounds across generations, remains a profound area of inquiry in understanding individual and collective well-being. This research investigates the multidimensional nature of transgenerational trauma, integrating insights from psychology, sociology, and neuroscience to unravel the mechanisms of trauma transmission and the development of resilience. By examining epigenetic processes, familial dynamics, and socio-historical contexts, the study highlights how traumatic experiences shape behaviors, beliefs, and coping strategies over time. It further explores resilience-building mechanisms, such as cultural practices, collective memory, and therapeutic interventions, that mitigate the effects of inherited trauma. Employing both qualitative and quantitative methodologies, including case studies and longitudinal surveys, this research presents a comprehensive framework for addressing transgenerational trauma and fostering intergenerational healing. The findings underscore the importance of interdisciplinary approaches in developing effective intervention strategies, emphasizing the role of community, storytelling, and systemic support in promoting psychological resilience. This work contributes to the growing discourse on trauma and resilience, offering actionable insights for clinicians, policymakers, and researchers dedicated to advancing mental health and societal healing.