Transient cerebellar mutism after evacuation of a spontaneous vermian haematoma

Sinha, Amitasha; Rajender, Y.; Dinakar, I

doi:10.1007/s003810050261

Cited by 29 publications

(12 citation statements)

References 11 publications

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“…Indeed, a review of the literature only reveals 9 cases of cerebellar mutism following posterior fossa lesions of vascular origin, including 2 adult cases [3, 4, 6,8,9,10, 41, 42] (table 2). In addition, 3 cases with so-called transient cerebellar mutism following vascular damage to cerebellar and/or adjacent structures of the cerebellum have been described.…”

Section: Discussionmentioning

confidence: 99%

“…Although in the majority of cases the PFS resulted from posterior fossa tumor resection (n = 203, 90%), other etiological causes have been described as well. A review of the literature since 1972 shows that only 10 (4.4%) of the 225 pediatric cases had a vascular etiology [3,4,5,6,7,8,9,10,11], 5 subjects (2.2%) had traumatic lesions [6,12,13,14] and 7 cases (3.1%) developed cerebellar mutism following an infection [15,16,17,18,19,20]. …”

Section: Introductionmentioning

confidence: 99%

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Posterior Fossa Syndrome after a Vermian Stroke: A New Case and Review of the Literature

et al. 2007

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The posterior fossa syndrome (PFS) is a well-known clinical consequence of posterior fossa surgery that has only been reported in a limited number of cases with a nontumoral etiology. It consists of transient cerebellar mutism, behavioral abnormalities and personality changes. We describe a 12-year-old child who developed transient cerebellar mutism associated with behavioral and emotional symptoms following rupture of a vermis arteriovenous malformation (AVM). Following the stroke, the girl experienced a 24-hour symptom-free interval. After that, she became mute and her emotional state was characterized by severe anxiety, irritability and withdrawal. After 3 days, mutism resolved and dysarthria became apparent. Two weeks after stroke, the AVM was surgically removed and the postoperative course was uneventful. This case is the first reported in which the PFS occurred after focal nonsurgically induced cerebellar damage.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Posterior Fossa Syndrome after a Vermian Stroke: A New Case and Review of the Literature

et al. 2007

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“…El primero en describirlo fue Rekate en 1985 2 ; principalmente como un déficit postoperatorio en cirugías de fosa posterior 3,4 , aunque también se ha descrito secundario a infecciones [5][6][7][8] , trauma 9,10 o eventos isquémicos [11][12][13] . Es una complicación relativamente común después de una cirugía de fosa posterior (se ha descrito una incidencia entre el 11 y el 29% de los casos) 4,14,15 aunque su verdadera incidencia es difícil de determinar debido a problemas en la terminología y una definición variable del síndrome 16 .…”

Section: Introductionunclassified

Tractografía de la vía dento-rubro-talámica en mutismo cerebeloso postoperatorio en niños con tumores de fosa posterior

Cohen-Scheihing

2015

Rev. chil. neuro-psiquiatr.

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“…39 Some authors regard CMS as a synonym for posterior fossa syndrome (PFS) and use the terms interchangeably, 55,82,109 while others believe that CM is a severe form of cerebellar dysarthria. 33,44,68,89,99,103,105 In 1998, Schmahmann and Sherman 84 introduced the term cerebellar cognitive affective syndrome to describe a constellation of neuropsychological findings in adult patients with diseases confined to the cerebellum. The major deficits involved impairment of executive functions, difficulties with spatial cognition, personality changes, and language deficits including agrammatism and dysprosodia.…”

Section: Definitionsmentioning

confidence: 99%

“…It usually appears as a consequence of posterior fossa surgery in children with cerebellar or fourth ventricle tumors. 52,82,108 Other causes that have been reported are infections, 15,19,24,26,72 posterior fossa hematomas (surgically removed 31,89 or not 60 ), arteriovenous malformations, 33,51,82 a brainstem tumor, 82 a pineal gland tumor, 23 and traumatic cerebellar injury. 15,82 Although this clinical entity is mainly seen in children, there are also reports of CM in adults.…”

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confidence: 99%

Cerebellar mutism

Pitsika¹,

Tsitouras²

2013

PED

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Mutism of cerebellar origin is a well-described clinical entity that complicates operations for posterior fossa tumors, especially in children. This review focuses on the current understanding of principal pathophysiological aspects and risk factors, epidemiology, clinical characteristics, treatment strategies, and outcome considerations. The PubMed database was searched using the term cerebellar mutism and relevant definitions to identify publications in the English-language literature. Pertinent publications were selected from the reference lists of the previously identified articles. Over the last few years an increasing number of prospective studies and reviews have provided valuable information regarding the cerebellar mutism syndrome. Importantly, the clarification of principal terminology that surrounds the wide clinical spectrum of the syndrome results in more focused research and more effective identification of this entity. In children who undergo surgery for medulloblastoma the incidence of cerebellar mutism syndrome was reported to be 24%, and significant risk factors so far are brainstem involvement and midline location of the tumor. The dentate-thalamo-cortical tracts and lesions that affect their integrity are considered significant pathophysiological issues, especially the tract that originates in the right cerebellar hemisphere. Moderate and severe forms of the cerebellar mutism syndrome are the most frequent types during the initial presentation, and the overall neurocognitive outcome is not as favorable as thought in the earlier publications. Advanced neuroimaging techniques could contribute to identification of high-risk patients preoperatively and allow for more effective surgical planning that should focus on maximal tumor resection with minimal risk to important neural structures. Properly designed multicenter trials are needed to provide stronger evidence regarding effective prevention of cerebellar mutism and the best therapeutic approaches for such patients with a combination of pharmacological agents and multidisciplinary speech and behavior augmentation.

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Transient cerebellar mutism after evacuation of a spontaneous vermian haematoma

Cited by 29 publications

References 11 publications

Posterior Fossa Syndrome after a Vermian Stroke: A New Case and Review of the Literature

Posterior Fossa Syndrome after a Vermian Stroke: A New Case and Review of the Literature

Tractografía de la vía dento-rubro-talámica en mutismo cerebeloso postoperatorio en niños con tumores de fosa posterior

Cerebellar mutism

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