Transient diabetes insipidus and acute fatty liver of pregnancy

Kennedy, Suzanne; Hall, Pauline de la Μ.; Seymour, A. E.; Hague, William

doi:10.1111/j.1471-0528.1994.tb11909.x

Cited by 93 publications

(34 citation statements)

References 24 publications

(31 reference statements)

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“…Extrahepatic complications may occur, which can be life-threatening [10,11] . The patients rarely develop pancreatitis, which can be severe.…”

Section: Discussionmentioning

confidence: 99%

Acute fatty liver of pregnancy associated with severe acute pancreatitis: A case report

Oliveira¹,

Moreira²,

Baima³

et al. 2014

WJH

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Acute fatty liver of pregnancy is a rare disease that affects women in the third trimester of pregnancy. Although infrequent, the disease can cause maternal mortality. The diagnosis is not always clear until the pregnancy is terminated, and significant complications, such as acute pancreatitis, can occur. Pancreatic involvement typically only occurs in severe cases after the development of hepatic and renal impairment. To date, little knowledge is available regarding how the disease causes pancreatitis. Treatment involves supportive measures and pregnancy interruption. In this report, we describe a case of a previously healthy 26-year-old woman at a gestational age of 27 wk and 6 d who was admitted with severe abdominal pain and vomiting. This case illustrates the clinical and laboratory overlap between acute fatty liver of pregnancy and pancreatitis, highlighting the difficulties in differentiating each disease. Furthermore, the hypothesis for this overlapping is presented, and the therapeutic options are discussed.

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“…Extrahepatic complications may occur, which can be life-threatening [10,11] . The patients rarely develop pancreatitis, which can be severe.…”

Section: Discussionmentioning

confidence: 99%

Acute fatty liver of pregnancy associated with severe acute pancreatitis: A case report

Oliveira¹,

Moreira²,

Baima³

et al. 2014

WJH

View full text Add to dashboard Cite

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“…Hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome, pre-eclampsia, thrombotic thrombocytopenia purpura and AFLP may all be a spectrum of the same illness. Extrahepatic complications include infection, intra-abdominal bleeding, central diabetes insipidus, and pancreatitis [13][14][15] . Laboratory abnormalities typically include serum aminotransferase elevations in the range of 1,000 IU/L.…”

Section: Discussionmentioning

confidence: 99%

Acute liver failure in the setting of herpes simplex virus and coexistent acute fatty liver of pregnancy

Wilder¹,

Chang

Cardona

et al. 2015

CRCP

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“…Besides placental vasopressinase activity, transient liver dysfunction may decrease the degradation of vasopressinase in the liver. This may explain the association of acute fatty liver of pregnancy and HELLP syndrome (288)(289)(290)(291). Therefore, women developing DI late in gestation should be screened for liver function abnormalities.…”

Section: Hypopituitarism and Pregnancymentioning

confidence: 99%

Pregnancy and pituitary disorders

Karaca¹,

Tanrıverdi²,

Ünlühızarcı³

et al. 2010

European Journal of Endocrinology

164

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Major hormonal changes emerge during pregnancy. The pituitary gland is one of the most affected organs with altered anatomy and physiology. The pituitary gland is enlarged as a result of lactotroph hyperplasia. Due to physiological changes in the pituitary and target hormone levels, binding globulins, and placental hormones, hormonal evaluation becomes more complex in pregnant women. As a consequence of physiological hormonal changes, the evaluation of pituitary functions in pregnant women is quite different from that done in the prepregnant state. Pituitary adenomas may cause problems by their hormone secretion that affects the mother and the fetus besides causing an increased risk of tumor growth. Furthermore, diagnosis, course, and treatment of pituitary diseases point out differences. The changes in anatomy and physiology of the pituitary gland during pregnancy are reviewed. Pituitary disorders namely Cushing's disease; acromegaly; prolactinoma; TSH-secreting, gonadotropin-producing, and clinically nonfunctioning adenomas; craniopharyngioma; and Sheehan's syndrome, which is one of the most common causes of hypopituitarism, lymphocytic hypophysitis, and hypopituitarism, in relation to pregnancy are discussed. Being aware of all this information will prevent any serious problems which mother and child will be exposed to.

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Transient diabetes insipidus and acute fatty liver of pregnancy

Cited by 93 publications

References 24 publications

Acute fatty liver of pregnancy associated with severe acute pancreatitis: A case report

Acute fatty liver of pregnancy associated with severe acute pancreatitis: A case report

Acute liver failure in the setting of herpes simplex virus and coexistent acute fatty liver of pregnancy

Pregnancy and pituitary disorders

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