Transient elastography using Fibroscan is the most reliable noninvasive method for the diagnosis of advanced fibrosis and cirrhosis in alcoholic liver disease
“…However, in terms of the performance for noninvasive prediction of liver fibrosis, FIB-4 does not surpass LS. 26,27 As a matter of fact, FIB-4 only provides the moderate degree of diagnostic value comparable to that of aspartate aminotransferase-to-platelet ratio index (APRI). 28 Nevertheless, FIB-4 has important advantages of good availability and cost-effectiveness as APRI which has recently been recommended in resourcelimited settings as a screening tool for the underlying fibrotic burden in patients with CHB according to the WHO guideline.…”
“…However, in terms of the performance for noninvasive prediction of liver fibrosis, FIB-4 does not surpass LS. 26,27 As a matter of fact, FIB-4 only provides the moderate degree of diagnostic value comparable to that of aspartate aminotransferase-to-platelet ratio index (APRI). 28 Nevertheless, FIB-4 has important advantages of good availability and cost-effectiveness as APRI which has recently been recommended in resourcelimited settings as a screening tool for the underlying fibrotic burden in patients with CHB according to the WHO guideline.…”
“…However, these two indices were reported with only limited diagnostic value in classifying advanced liver fibrosis in ALD. [2][3][4][5] This point of view was also recommeded in a recent guideline by European Association for Study of Liver. 6 Second, learning from data in table 1 and table 3, there were 520 aspirin users including 132 patients with virus hepatitis, 109 patients with ALD and 315 patients with NASH.…”
“…TE can be used to exclude cirrhosis in patients with alcoholic liver disease, provided that acute alcoholic hepatitis is not present (LoE 2b, GoR B) [56,214,219,220]. Strong consensus (15/0/0, 100 %)…”
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.