ABSTRACT1 Earthquake Prediction Research Center, Tokai University, Shizuoka, Japan * Corresponding author address: Prof. S. Uyeda, Earthquake Prediction Research Center, Tokai University, Shimizu Orido, Shizuoka, Japan; Mitigation of seismic hazards requires integration of science and human action, namely the science of earthquakes, anti-seismic engineering and socio-political measures. In this paper, we will be primarily examining the problem of saving human life from earthquakes. Loss of human life from earthquakes is caused overwhelmingly by the collapse of houses and buildings within less than a few minutes of the main shocks. When structural damage is reduced, most other seismic hazards will also be reduced. On top of that, if short-term prediction could be made, casualties would be further reduced dramatically. We review the state of the art in short-term prediction, in particular recent progress in approaches using electromagnetic phenomena.The RIKEN International Frontier Research Project on Earthquakes (IFREQ) has demonstrated the existence of pre-seismic ultra-low frequency (ULF) geo-electric potential changes, a claim that has long been made by the Greek VAN group. In addition, IFREQ has been able to verify the precursory signatures of ULF geomagnetic variations. A review is also made for another promising method using pre-seismic over-the-horizon transmission of VHF (~100MHz) FM radio waves. Thus, the reinforcement of existing structures and enhancement of short-term prediction research are the two keys for seismic hazard mitigation.