This manuscript presents a study of three-dimensional MHD Maxwell nanofluid flow across a slendering stretched surface with Joule heating. The impact of binary chemical reactions, heat generation, thermal radiation, and thermophoretic effect is also taken into consideration. The multiple slip boundary conditions are utilized at the boundary of the surface. The appropriate similarity variable is used to transfer the flow modeled equations into ODEs, which are numerically solved by the utilization of the MATLAB bvp4c algorithm. The involved parameter's impact on the concentration, velocity, and temperature distribution are scrutinized with graphs. The transport rates (mass, heat) are also investigated using the same variables, with the results reported in tabulated form. It is seen that the fluid relaxation, magnetic, and wall thickness characteristics diminish the velocities of fluid. Further, the velocity, concentration, and temperature slip parameters reduce the velocities of fluid, temperature, and concentration distribution. The results are compared to existing studies and showed to be in dependable agreement.