Transient impotence after transrectal ultrasound‐guided prostate biopsy

Akyol, İlker; Adayener, Cüneyt

doi:10.1002/jcu.20417

Cited by 7 publications

(7 citation statements)

References 6 publications

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“…Although there was a significant difference in the timing of re‐evaluation between men diagnosed with PCa and those with benign disease on biopsy, we do not believe that this explains the differences in erectile function that were observed between the groups. This is supported by the fact that most men with a positive biopsy were re‐evaluated at ∼7.5 weeks after PNBx (Table ), a time when the effects of periprostatic anaesthetic agents should be diminished . In addition, our multivariate analyses found no significant associations between the timing of erectile function assessment and a meaningful change in IIEF score.…”

Section: Discussionmentioning

confidence: 57%

“…It has been suggested that men may experience ED after PNBx. It appears that for the majority of these men, this decrease in erectile function is transient and returns to baseline by 4–6 weeks after the procedure . In fact, only a small percentage of men (8–10%) will continue to experience ED more than 3 months after PNBx .…”

Section: Discussionmentioning

confidence: 97%

“…local anaesthestic, number of biopsies, time after the procedure, etc.) , to our knowledge no study has addressed these issues in relationship to PCa diagnosis. Reasons for this include the fact that the urinary symptoms and erectile function of most men are evaluated and treated after a PCa diagnosis, and that data regarding ED and LUTS are not systematically obtained with validated questionnaires by most screening studies or cancer registries.…”

Section: Discussionmentioning

confidence: 99%

“…Several studies have suggested that PNBx is associated with erectile dysfunction (ED) and LUTS . These changes have been attributed to periprostatic nerve anaesthesia and injury , saturation PNBx , and serial PNBx . By contrast, other studies have not found a relationship between ED and PNBx .…”

Section: Introductionmentioning

confidence: 99%

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Prostate cancer diagnosis is associated with an increased risk of erectile dysfunction after prostate biopsy

et al. 2012

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What's known on the subject? and What does the study add? There have been several studies that have suggested there may be a relationship between prostate biopsy and erectile function and LUTS. Previous studies have suggested a specific association between the type of local anaesthesia administered and/or the number of biopsies performed. Other studies have suggested an exacerbation of LUTS after prostate biopsy. The present study identifies a positive cancer diagnosis as a novel characteristic that may explain a relationship between biopsy and worsening erectile function. Objective To evaluate prospectively the characteristics, erectile function and lower urinary tract symptoms (LUTS) of men undergoing prostate needle biopsy (PNBx). Patients and Methods From 2008 to 2011, 134 men were prospectively administered the International Index of Erectile Function (IIEF), American Urological Association Symptom Index (AUA‐SI), and quality‐of‐life (QoL) questionnaires before and after undergoing a single 12‐core PNBx. Comparisons of IIEF and AUA‐SI scores before and after PNBx, based upon baseline characteristics and prostate cancer (PCa) diagnosis, were performed. Univariable and multivariable logistic regression models were used to characterize predictors of change in IIEF scores. Results In the 85 men who fulfilled the inclusion criteria, there were no significant differences between the mean (sd) total pre‐biopsy and the mean (sd) post‐biopsy IIEF scores: 57.8 (12.9) vs 54.3 (17.2). Subgroup analysis showed that men who had biopsy‐proven PCa had significantly greater changes in their post‐biopsy IIEF scores compared with men without (−10.1 vs. 1.0; P < 0.001). After specific analyses of the IIEF domains in these groups we found significant decreases in every domain, including erectile function (P = 0.01). On multivariate analyses, only PCa diagnosis was associated with a significant change in IIEF (odds ratio 7.2; P = 0.003). There were no differences in AUA‐SI or QoL scores in the overall population or in subgroups. Conclusions Cancer diagnosis appears to have an adverse effect on the erectile function of men undergoing PNBx but no effect on LUTS. This study highlights a potential negative psychological confounder that may influence erectile function before the treatment of PCa. Additional prospective trials evaluating these relationships are warranted.

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Section: Discussionmentioning

confidence: 57%

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Prostate cancer diagnosis is associated with an increased risk of erectile dysfunction after prostate biopsy

et al. 2012

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“…111 Erectile dysfunction was noted in 2.2% of men in a study be Akyol and Adayener possibly due to nerve injury caused by the biopsy needle. 112 However, in a study by Helfand et al, cancer diagnosis appears to have an adverse effect on the erectile function of men undergoing prostate biopsy but no effect on lower urinary tract symptoms. 113 Similarly, serial prostate biopsies appear to have an adverse effect on erectile function in men with prostate cancer on active surveillance but do not affect lower urinary tract symptoms.…”

Section: Complicationsmentioning

confidence: 96%

Optimization of Prostate Biopsy

Bjurlin

Wysock

Taneja

2014

Urologic Clinics of North America

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The Impact of Prostate Biopsy on Urinary Symptoms, Erectile Function, and Anxiety

2012

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Transrectal ultrasound-guided prostate needle biopsy (PB) is considered the gold standard for the diagnosis of prostate cancer. Recently, lower urinary tract symptoms and erectile dysfunction have been reported following PB. We reviewed the literature on PB and these symptoms and summarized known findings between these conditions and other variables, such as periprostatic nerve block, saturation biopsy, serial biopsies, and psychological factors associated with PB and cancer. A PubMed search was performed using keywords "prostate biopsy," "complications," "erectile dysfunction," "lower urinary tract symptoms," "anxiety," and "quality of life." Eleven key papers are discussed and personal experience is drawn upon. Based upon available evidence, PB appears to be associated with short-term exacerbation of urinary symptoms in some men, as well as associated with anxiety and temporary erectile dysfunction, without a distinct relationship to periprostatic nerve block or the number of cores biopsied. Additional studies are warranted to determine the definitive etiology of these symptoms and to determine if interventions could reduce patient morbidity. In the interim, patients should be educated and counseled about these risks before undergoing PB.

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Transient impotence after transrectal ultrasound‐guided prostate biopsy

Cited by 7 publications

References 6 publications

Prostate cancer diagnosis is associated with an increased risk of erectile dysfunction after prostate biopsy

Prostate cancer diagnosis is associated with an increased risk of erectile dysfunction after prostate biopsy

Optimization of Prostate Biopsy

The Impact of Prostate Biopsy on Urinary Symptoms, Erectile Function, and Anxiety

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