2010
DOI: 10.1177/112070001002000301
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Transient Osteoporosis of the Hip

Abstract: Transient osteoporosis of the hip (TOH) is not an uncommon condition, usually with a benign course. The syndrome classically affects women during the last trimester of pregnancy, but also middle aged men. Recently, TOH has been described in non pregnant women. The pathophysiology of the disease is uncertain, though several hypotheses have been suggested. Joint pain is the main symptom. TOH is a self-limited cond… Show more

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Cited by 28 publications
(10 citation statements)
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“…The pathophysiology of TOH is still not completely understood -current theories postulate the progression to occur in three stages, summarized in Figure 4 [7][8][9][10]. With the advent of MRI, the observed BME became a cornerstone of the pathogenesis of the disorder, although the mechanism leading to this finding is still debated.…”
Section: Discussionmentioning
confidence: 99%
“…The pathophysiology of TOH is still not completely understood -current theories postulate the progression to occur in three stages, summarized in Figure 4 [7][8][9][10]. With the advent of MRI, the observed BME became a cornerstone of the pathogenesis of the disorder, although the mechanism leading to this finding is still debated.…”
Section: Discussionmentioning
confidence: 99%
“…Plain radiographs in early stage of the disease are normal, but within 4-8 weeks, there is profound osteopenia of the femoral head and neck as a result of elevated rate of bone turnover. Classically, TOH in pregnancy is self-limiting; clinical and radiological resolution occurs in 6-8 months after delivery [24,36]. The prognosis is good if recognized early.…”
Section: Hip Painmentioning
confidence: 97%
“…Whether it is normally bilateral in pregnancy, it is most often seen as unilateral in the other presentation. In most cases no triggering events are detected, but theoretically any insult such as previous trauma (including fracture, altered biomechanics, bone edema, subchondral lesions), osteoarthritis, inflammatory diseases (i.e., arthropathies, enthesopathies, gout), vascular lesions (i.e., avascular necrosis, algoneurodystrophy), infective lesions (viral, diabetic foot, osteomyelitis), iatrogen lesions (previous surgery or radiotherapy), neoplastic lesions and other variables (alcoholic consumption, smoking, steroids, hypothyroidism, low testosterone, low vitamin D, osteogenesis imperfecta, pregnancy or breastfeeding) may determine a condition of transient bone edema of the hip [6][7][8][9][10].…”
Section: Epidemiology and Etiologymentioning
confidence: 99%