Transient Protein-Losing Enteropathy and Enlarged Gastric Rugae in Childhood

Stillman, Alfred E.

doi:10.1001/archpedi.1981.02130250017007

Cited by 13 publications

(17 citation statements)

References 21 publications

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“…Among the numerous factors considered, allergy and/or infection seem to be the most likely. Viral infection and specifically CMV infection, preceding or concomitant with the disease has been de-scribed in many of the reported cases [2,3]. The frequent peripheral eosinophilia and gastric mucosal infiltration with eosinophils reported in the literature could favor allergy [1, 2].…”

Section: Discussionmentioning

confidence: 99%

Transient protein-losing gastropathy (Menetrier's disease) in childhood

Bar-Ziv¹,

Barki²,

Weizman³

et al. 1988

Pediatr Radiol

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Two cases of transient protein-losing gastropathy (PLG) or Menetrier's disease in childhood are described. Both cases presented with an abrupt onset of edema due to hypoalbuminemia and were diagnosed by an upper gastrointestinal series. One of the cases was further diagnosed and followed by ultrasound. We believe that this is the first description of the ultrasonic picture of transient PLG in children. In both cases complete recovery was evident after a few weeks.

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Section: Discussionmentioning

confidence: 99%

Transient protein-losing gastropathy (Menetrier's disease) in childhood

Bar-Ziv¹,

Barki²,

Weizman³

et al. 1988

Pediatr Radiol

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“…Other conditions with a similar roentgenographic appearance must be eliminated from the differential diagnosis of thickened rugal folds (5)(6)(7)(8)(17)(18)(19). Gastric malignancy-lymphoma, sarcoma, or carcinoma-is quite 218 D.BENECK rare in childhood, is usually associated with involvement of other organs, and lacks features of hyposecretion.…”

Section: Discussionmentioning

confidence: 99%

“…There are numerous reports of hypertrophic gastropathy associated with cytomegalovirus (4, 6,9,15,18,[26][27][28][29] and with other viruses [parainfluenza (16) and herpes simplex (28)]. Coincidentally, several of these patients (7 of 13) also had peripheral eosinophilia.…”

Section: Discussionmentioning

confidence: 99%

Hypertrophic Gastropathy in a newborn: A Case Report and Review of the Literature

Beneck

1994

Pediatric Pathology

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A newborn with hypoalbuminemia, hematochezia, and hypertrophic gastropathy is described. These features are similar to those reported in association with prostaglandin therapy in newborns, as well as those described in so-called Ménétrier's disease. Very few cases of hypertrophic gastropathy have been reported in children and fewer still verified histologically; only three other cases have been reported in newborns. The clinical and pathologic features of hypertrophic gastropathy in children, as well as its close association with eosinophilic gastroenteritis and with prostaglandin therapy, are discussed.

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“…In adults, the course is more often severe, with persistent protein-losing enteropathy which may require gastrectomy (12,13). The cause of Menetrier's disease remains uncertain; infectious (2,5,7,8,10), allergic (1,11), and immunologic (3,14) causes have been postulated. In this study, the association of cytomegalovirus (CMV) infection with a protein-losing enteropathy secondary to hypertrophic gastropathy was demonstrated by in situ hybridization.…”

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confidence: 99%