Transient serous retinal detachment after photodynamic therapy for polypoidal choroidal vasculopathy

Tobita, Hideaki; Ohno‐Matsui, Kyoko; Ogawa, Manabu; Kaneko, Yuh; Shimada, Noriaki; Mochizuki, Manabu

doi:10.1007/s10384-008-0595-x

Cited by 3 publications

(1 citation statement)

References 5 publications

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“…Increased exudation has been reported following PDT of ocular conditions other than tumors, including choroidal neovascular membrane (CNVM) and polypoidal choroidal vasculopathy 22–25. Reports of increased leakage after PDT from intraocular tumors are limited to juxtapapillary retinal hemangioblastoma 1316.…”

Section: Discussionmentioning

confidence: 99%

Transient increased exudation after photodynamic therapy of intraocular tumors

Mashayekhi

Shields

2013

Middle East Afr J Ophthalmol

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To report transient increased exudation after photodynamic therapy (PDT) of three different intraocular tumors (retinal hemangioblastoma, retinal astrocytoma, amelanotic choroidal melanoma). PDT with verteporfin (6 mg/m2 body surface area) was delivered at a dose of 50 J/cm2 and intensity of 600 mW/cm2 over 83 s. All patients experienced decreased vision within a few days following PDT. Optical coherence tomography showed development of subfoveal fluid in all cases and noncystoid intraretinal edema in the eye with juxtapapillary retinal hemangioblastoma. There was complete absorption of retinal/subretinal fluid with improvement of visual acuity to 20/20 in all cases between 3 weeks to 4 months after PDT.

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Section: Discussionmentioning

confidence: 99%

Transient increased exudation after photodynamic therapy of intraocular tumors

Mashayekhi

Shields

2013

Middle East Afr J Ophthalmol

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N-acetylcysteine protects against chorioretinal damage induced by photodynamic therapy for experimental choroidal neovascularization in a rat model

Kim

Moon

2018

Photodiagnosis and Photodynamic Therapy

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Extensive Serous Retinal Detachment after Photodynamic Therapy for Polypoidal Choroidal Vasculopathy

Lee

Nam

2016

J Retin

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Purpose:To report a case with extensive serous retinal detachment (SRD) after photodynamic therapy (PDT) for polypoidal choroidal vasculopathy (PCV) Case summary: A 72 year old man visited our clinic complaining of visual disturbance in the left eye for 1 week. Visual acuity (VA) was finger counting at 30 cm in the left eye. The fundus was invisible due to vitreous hemorrhage, and so vitrectomy was performed; atrophic scar on the posterior pole and extensive subretinal hemorrhage over the inferior retina were seen during surgery. One week after surgery, best corrected visual acuity was 0.075. Three weeks after vitrectomy, large pigment epithelial detachment superior to the fovea and cystic lesions in the retina were seen on optical coherence tomography, and a branching vascular network and polyps were found on indocyanine green angiography. Thus, PDT was performed for PCV treatment. Two weeks after PDT, the patient complained of decreased vision and superior visual field defect. On fundus examination, extensive retinal detachment (RD) reaching below the fovea was found, but no retinal break or hole was found. Thus, intravitreal anti-vascular endothelial growth factor injection had been performed at 5 months.However, RD gradually progressed to fovea and subretinal fibrosis was developed. Surgical treatment with retinotomy, subretinal fluid drainage and fluid-gas exchange was performed. The retina was flattened after surgery and VA recovered to 0.1. Conclusions:Transient SRD is often seen after PDT for age related macular degeneration or PCV, but extensive SRD is very rare. Surgical treatment may be another treatment option in such cases.

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Transient serous retinal detachment after photodynamic therapy for polypoidal choroidal vasculopathy

Cited by 3 publications

References 5 publications

Transient increased exudation after photodynamic therapy of intraocular tumors

Transient increased exudation after photodynamic therapy of intraocular tumors

N-acetylcysteine protects against chorioretinal damage induced by photodynamic therapy for experimental choroidal neovascularization in a rat model

Extensive Serous Retinal Detachment after Photodynamic Therapy for Polypoidal Choroidal Vasculopathy

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